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PTPRN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6004162

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PTPRN2, Polyclonal Antibody
Full Product Name
PTPRN2, NT (PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoantigen-related protein, Phogrin)
Product Gene Name
Product Synonym Names
Anti -PTPRN2, NT (PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoantigen-related protein, Phogrin)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
111,271 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (157331750..158380482, complement). Location: 7q36
OMIM
601698
3D Structure
ModBase 3D Structure for Q92932
Immunogen
PTPRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the N-terminal region of human PTPRN2.
Applications Tested/Suitable for anti-PTPRN2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PTPRN2 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-PTPRN2 antibody

PTPRN2 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PTPRN2 antibody detected the PTPRN2 protein (arrow).
Rabbit Anti-PTPRN2 Polyclonal Antibody – Cat# MBS6004162

Other Notes

Small volumes of anti-PTPRN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPRN2 purchase

MBS6004162 is an antibody targeting PTPRN2. Also known as PTPRN2, NT (PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoantigen-related protein, Phogrin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPRN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
PTPRN2 protein
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, N polypeptide 2
NCBI Official Symbol
PTPRN2
NCBI Official Synonym Symbols
IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase N2
UniProt Synonym Protein Names
Islet cell autoantigen-related protein; IAR; ICAAR; Phogrin
UniProt Gene Name
PTPRN2
UniProt Synonym Gene Names
KIAA0387; R-PTP-N2; IAR; ICAAR
UniProt Entry Name
PTPR2_HUMAN
NCBI Protein Information
receptor-type tyrosine-protein phosphatase N2; phogrin; tyrosine phosphatase IA-2 beta; islet cell autoantigen-related protein; protein tyrosine phosphatase receptor pi; IAR/receptor-like protein-tyrosine phosphatase

UniProt Comments for PTPRN2

PTPRN2: Implicated in development of nervous system and pancreatic endocrine cells. Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: integral to plasma membrane; endoplasmic reticulum lumen; terminal button; receptor complex; secretory granule

Molecular Function: transmembrane receptor protein tyrosine phosphatase activity

Biological Process: protein amino acid dephosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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