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QTRT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6339479

tRNA-guanine transglycosylase (TGT; EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a… More details

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Product Overview

Online Datasheet in PDF
Product Name
QTRT1, Polyclonal Antibody
Full Product Name
QTRT1, CT (QTRT1, TGT, TGUT, Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase) (MaxLight 750)
Product Gene Name
Product Synonym Names
QTRT1; TGT; TGUT; Queuine tRNA-ribosyltransferase; Guanine insertion enzyme; tRNA-guanine transglycosylase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
24,015 Da
OMIM
609615
3D Structure
ModBase 3D Structure for Q9BXR0
Immunogen
QTRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human QTRT1.
Conjugate
MaxLight750
Note
Preservative Free
Applications Tested/Suitable for anti-QTRT1 antibody
Western Blot (WB), FLISA
Application Notes for anti-QTRT1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-QTRT1 antibody

Chen, Y.C., et al. RNA 16(5):958-968(2010). Deshpande, K.L., et al. Gene 265 (1-2), 205-212 (2001).

Other Notes

Small volumes of anti-QTRT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for QTRT1 purchase

MBS6339479 is an antibody targeting QTRT1. Also known as QTRT1, CT (QTRT1, TGT, TGUT, Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase) (MaxLight 750). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for QTRT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
queuine tRNA-ribosyltransferase
NCBI Official Synonym Full Names
queuine tRNA-ribosyltransferase catalytic subunit 1
NCBI Official Symbol
QTRT1
NCBI Official Synonym Symbols
TGT; TGUT; FP3235
UniProt Protein Name
Queuine tRNA-ribosyltransferase
UniProt Synonym Protein Names
Guanine insertion enzyme; tRNA-guanine transglycosylase
UniProt Gene Name
QTRT1
UniProt Synonym Gene Names
TGT; TGUT
UniProt Entry Name
TGT_HUMAN
NCBI Protein Information
queuine tRNA-ribosyltransferase

UniProt Comments for QTRT1

QTRT1: Interacts with QTRTD1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). Belongs to the queuine tRNA-ribosyltransferase family.

Protein type: EC 2.4.2.29; Mitochondrial; RNA processing; Transferase

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; mitochondrial outer membrane

Molecular Function: protein heterodimerization activity; protein homodimerization activity; queuine tRNA-ribosyltransferase activity

Biological Process: queuosine biosynthetic process; tRNA modification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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