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QTRT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9455035

This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs… More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
QTRT1, Polyclonal Antibody
Full Product Name
QTRT1 Conjugated Antibody
Product Gene Name
Product Synonym Names
TGT; TGUT; FP3235
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Specificity
The antibody detects endogenous levels of total QTRT1 protein.
Preparation and Storage
Store at 4 degree C for 6 months.
Molecular Weight
24,015 Da
OMIM
609615
3D Structure
ModBase 3D Structure for Q9BXR0
Immunogen
Fusion protein of human QTRT1
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Applications Tested/Suitable for anti-QTRT1 antibody
Most Applications
Application Notes for anti-QTRT1 antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-QTRT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for QTRT1 purchase

MBS9455035 is an antibody targeting QTRT1. Also known as QTRT1 Conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for QTRT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens queuine tRNA-ribosyltransferase 1, mRNA
NCBI Official Synonym Full Names
queuine tRNA-ribosyltransferase catalytic subunit 1
NCBI Official Symbol
QTRT1
NCBI Official Synonym Symbols
TGT; TGUT; FP3235
UniProt Protein Name
Queuine tRNA-ribosyltransferase
UniProt Synonym Protein Names
Guanine insertion enzyme; tRNA-guanine transglycosylase
UniProt Gene Name
QTRT1
UniProt Synonym Gene Names
TGT; TGUT
UniProt Entry Name
TGT_HUMAN
NCBI Protein Information
queuine tRNA-ribosyltransferase

UniProt Comments for QTRT1

QTRT1: Interacts with QTRTD1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). Belongs to the queuine tRNA-ribosyltransferase family.

Protein type: EC 2.4.2.29; Mitochondrial; RNA processing; Transferase

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; mitochondrial outer membrane

Molecular Function: protein heterodimerization activity; protein homodimerization activity; queuine tRNA-ribosyltransferase activity

Biological Process: queuosine biosynthetic process; tRNA modification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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