Rabbit Anti-RAB3B Polyclonal Antibody – Cat# MBS6339774

RAB3B Antibody – Rabbit Polyclonal

Name: RAB3B Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6339774
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6339774

Protein transport. It probably is involved in vesicular traffic (By similarity). More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB3B, Polyclonal Antibody

Full Product Name

RAB3B, CT (RAB3B, Ras-related protein Rab-3B) (MaxLight 550)

Product Gene Name

anti-RAB3B antibody

Product Synonym Names

RAB3B; Ras-related protein Rab-3B

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

24,758 Da

OMIM

179510

3D Structure

ModBase 3D Structure for P20337

Immunogen

RAB3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from the C-terminal region of human RAB3B.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-RAB3B antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-RAB3B antibody

Western Blot (WB), FLISA

Application Notes for anti-RAB3B antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RAB3B antibody

Piper Hanley, K., et al. J. Endocrinol. 207(2):151-161(2010). Chung, C.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 106(52):22474-22479(2009). Zou, L., et al. Proc. Natl. Acad. Sci. U.S.A. 106(37):15801-15806(2009). Rotondo, F., et al. Appl. Immunohistochem. Mol. Morphol. 17(3):185-188(2009). Lamesch, P., et al. Genomics 89(3):307-315(2007).

Other Notes

Small volumes of anti-RAB3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB3B purchase

MBS6339774 is an antibody targeting RAB3B. Also known as RAB3B, CT (RAB3B, Ras-related protein Rab-3B) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB3B. It may not necessarily be applicable to this product.

NCBI GI #

19923750

NCBI GeneID

5865

NCBI Accession #

NP_002858.2

UniProt Primary Accession #

P20337

UniProt Secondary Accession #

Q5VUL2; Q9BSI1

UniProt Related Accession #

P20337

GenBank Nucleotide #

NM_002867.3

NCBI Official Full Name

ras-related protein Rab-3B

NCBI Official Synonym Full Names

RAB3B, member RAS oncogene family

NCBI Official Symbol

RAB3B

UniProt Protein Name

Ras-related protein Rab-3B

Protein Family

Ras-related protein

UniProt Gene Name

RAB3B

UniProt Entry Name

RAB3B_HUMAN

NCBI Protein Information

ras-related protein Rab-3B; brain antigen RAB3B

UniProt Comments for RAB3B

RAB3B: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 1p32-p31

Cellular Component: synaptic vesicle; secretory granule membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; cytosol; endosome; vesicle

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding

Biological Process: regulation of exocytosis; antigen processing and presentation; intracellular protein transport; synaptic vesicle exocytosis; positive regulation of dopamine uptake; protein secretion; peptidyl-cysteine methylation; Rab protein signal transduction; vesicle docking during exocytosis

Research Articles on RAB3B

1. The structure of Rab3B:GDP complex was solved to 1.9A resolution and the structural base comparison with other Rab3 members provides a structural basis for the GDP/GTP switch in controlling the activity of small GTPase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB3B antibody

Reference Product	PubMed Publications
PIGR antibody	>1 publications with RAB3B and PIGR

Pathways associated with anti-RAB3B antibody

Products by Pathway	Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram

Diseases associated with anti-RAB3B antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with RAB3B and Nervous System Diseases
Breast Neoplasms Antibodies	>2 publications with RAB3B and Breast Neoplasms
Inflammation Antibodies	>2 publications with RAB3B and Inflammation
Disease Models, Animal Antibodies	>1 publications with RAB3B and Disease Models, Animal
Ovarian Neoplasms Antibodies	>1 publications with RAB3B and Ovarian Neoplasms
Fibrosis Antibodies	>1 publications with RAB3B and Fibrosis
Necrosis Antibodies	>1 publications with RAB3B and Necrosis
Drug-Induced Liver Injury Antibodies	>1 publications with RAB3B and Drug-Induced Liver Injury

Organs/Tissues associated with anti-RAB3B antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>31 publications with RAB3B and Brain
Nerve Antibodies	>13 publications with RAB3B and Nerve
Pituitary Gland Antibodies	>11 publications with RAB3B and Pituitary Gland
Pancreas Antibodies	>7 publications with RAB3B and Pancreas
Liver Antibodies	>5 publications with RAB3B and Liver
Bone Marrow Antibodies	>4 publications with RAB3B and Bone Marrow
Bone Antibodies	>4 publications with RAB3B and Bone
Adrenal Gland Antibodies	>3 publications with RAB3B and Adrenal Gland
Lung Antibodies	>3 publications with RAB3B and Lung
Vascular Antibodies	>3 publications with RAB3B and Vascular