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RAD54B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6458635

MBS6458635 is an antibody targeting RAD54B. Also known as RAD54B (DNA Repair and Recombination Protein RAD54B, 364-, RAD54 Homolog B, RAD54B) (MaxLight 750). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAD54B, Polyclonal Antibody
Full Product Name
RAD54B (DNA Repair and Recombination Protein RAD54B, 364-, RAD54 Homolog B, RAD54B) (MaxLight 750)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human RAD54B. Species Crossreactivity: human
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
102,967 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (95384188..95487343, complement). Location: 8q22.1
OMIM
604289
3D Structure
ModBase 3D Structure for Q9Y620
Immunogen
KLH conjugated synthetic peptide corresponding to aa68-102 at the N-terminal region of human RAD54B.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-RAD54B antibody

Applications Tested/Suitable for anti-RAD54B antibody
Western Blot (WB)
Application Notes for anti-RAD54B antibody
WB: 1:2000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RAD54B antibody

Hiramoto T., et al. Oncogene 18:3422-3426(1999). Li W.B., et al. Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. Nusbaum C., et al. Nature 439:331-335(2006). Tanaka K., et al. J. Biol. Chem. 275:26316-26321(2000). Miyagawa K., et al. EMBO J. 21:175-180(2002).

Other Notes

Small volumes of anti-RAD54B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAD54B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA repair and recombination protein RAD54B isoform 3
NCBI Official Synonym Full Names
RAD54 homolog B (S. cerevisiae)
NCBI Official Symbol
RAD54B
NCBI Official Synonym Symbols
RDH54
UniProt Protein Name
DNA repair and recombination protein RAD54B
UniProt Synonym Protein Names
RAD54 homolog B
UniProt Gene Name
RAD54B
UniProt Entry Name
RA54B_HUMAN
NCBI Protein Information
DNA repair and recombination protein RAD54B

NCBI Summary for RAD54B

The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]
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UniProt Comments for RAD54B

RAD54B: Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group. Belongs to the SNF2/RAD54 helicase family.

Protein type: EC 3.6.1.-; EC 3.6.4.-; Helicase; DNA repair, damage

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: nucleus

Molecular Function: DNA helicase activity; DNA binding; DNA translocase activity; RNA helicase activity; ATP binding

Biological Process: mitotic recombination; meiotic recombination; DNA duplex unwinding; double-strand break repair via homologous recombination

Disease: Lymphoma, Non-hodgkin, Familial
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAD54B antibody

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