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RASGRP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7603366

MBS7603366 is an antibody targeting RASGRP3. Also known as RASGRP3 Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RASGRP3, Polyclonal Antibody
Full Product Name
RASGRP3 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
78,203 Da
OMIM
609531
Immunogen
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-RASGRP3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-RASGRP3 antibody

Immunohistochemistry of paraffin-embedded human ovary tumor slide using MBS7603366 (RASGRP3 Antibody) at dilution of 1:50
Rabbit Anti-RASGRP3 Polyclonal Antibody – Cat# MBS7603366

Western Blot (WB) of anti-RASGRP3 antibody

RAW264.7 cells were subjected to SDS PAGE followed by western blot with MBS7603366 (RASGRP3 antibody) at dilution of 1:800
Rabbit Anti-RASGRP3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS7603366

Other Notes

Small volumes of anti-RASGRP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RASGRP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras guanyl-releasing protein 3 isoform 1
NCBI Official Synonym Full Names
RAS guanyl releasing protein 3
NCBI Official Symbol
RASGRP3
NCBI Official Synonym Symbols
GRP3
UniProt Protein Name
Ras guanyl-releasing protein 3
UniProt Synonym Protein Names
Calcium and DAG-regulated guanine nucleotide exchange factor III; Guanine nucleotide exchange factor for Rap1
UniProt Gene Name
RASGRP3
UniProt Synonym Gene Names
GRP3; KIAA0846
UniProt Entry Name
GRP3_HUMAN
NCBI Protein Information
ras guanyl-releasing protein 3

NCBI Summary for RASGRP3

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
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UniProt Comments for RASGRP3

RASGRP3: Guanine nucleotide exchange factor (GEF) for Ras and Rap1. Belongs to the RASGRP family.

Protein type: GEFs; GEFs, Ras

Chromosomal Location of Human Ortholog: 2p25.1-p24.1

Cellular Component: integral to plasma membrane; perinuclear region of cytoplasm; plasma membrane

Molecular Function: calcium ion binding; diacylglycerol binding; GTPase activator activity; guanyl-nucleotide exchange factor activity; kinase binding; protein binding; Ras GTPase binding; Ras guanyl-nucleotide exchange factor activity; signal transducer activity

Biological Process: MAPKKK cascade; positive regulation of GTPase activity; Ras protein signal transduction; small GTPase mediated signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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