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RASSF3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6340519

The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including… More details

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Product Overview

Online Datasheet in PDF
Product Name
RASSF3, Polyclonal Antibody
Full Product Name
RASSF3, NT (RASSF3, Ras association domain-containing protein 3) (PE)
Product Gene Name
Product Synonym Names
RASSF3; Ras association domain-containing protein 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
10,265 Da
OMIM
607019
3D Structure
ModBase 3D Structure for Q86WH2
Immunogen
RASSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-36 amino acids from the N-terminal region of human RASSF3.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-RASSF3 antibody

Applications Tested/Suitable for anti-RASSF3 antibody
Western Blot (WB), FLISA
Application Notes for anti-RASSF3 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-RASSF3 antibody

RASSF3 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RASSF3 antibody detected the RASSF3 protein (arrow).
Rabbit Anti-RASSF3 Polyclonal Antibody – Cat# MBS6340519

Product References and Citations for anti-RASSF3 antibody

Davila, S., et al. Genes Immun. 11(3):232-238(2010). Jacquemart, I.C., et al. Int. J. Oncol. 34(2):517-528(2009). Fujita, H., et al. J. Biol. Chem. 280(6):5022-5031(2005). Tommasi, S., et al. Oncogene 21(17):2713-2720(2002).

Other Notes

Small volumes of anti-RASSF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RASSF3 purchase

MBS6340519 is an antibody targeting RASSF3. Also known as RASSF3, NT (RASSF3, Ras association domain-containing protein 3) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RASSF3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras association domain-containing protein 3
NCBI Official Synonym Full Names
Ras association (RalGDS/AF-6) domain family member 3
NCBI Official Symbol
RASSF3
NCBI Official Synonym Symbols
RASSF5
UniProt Protein Name
Ras association domain-containing protein 3
UniProt Gene Name
RASSF3
UniProt Entry Name
RASF3_HUMAN
NCBI Protein Information
ras association domain-containing protein 3; Ras association (RalGDS/AF-6) domain family 3

NCBI Summary for RASSF3

The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
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UniProt Comments for RASSF3

RASSF3: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q14.2

Cellular Component: microtubule; cytoplasm; plasma membrane

Molecular Function: identical protein binding; protein binding

Biological Process: signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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