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RASSF6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150937

RASSF6 Antibody: RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein /… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RASSF6, Polyclonal Antibody
Full Product Name
RASSF6 Antibody
Product Gene Name
Product Synonym Names
RASSF6; Ras association domain-containing protein 6; Ras association (RalGDS/AF-6) domain family member 6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
RASSF6 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.
Preparation and Storage
RASSF6 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
RASSF6 peptide (MBS151875) is used for blocking the activity of RASSF6 antibody (MBS150937)
Molecular Weight
35,809 Da
OMIM
612620
3D Structure
ModBase 3D Structure for Q6ZTQ3
Conjugate
Unconjugated
Immunogen
RASSF6 antibody was raised against a 14 amino acid synthetic peptide near the center of human RASSF6.
Buffer
RASSF6 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-RASSF6 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-RASSF6 antibody
RASSF6 antibody can be used for detection of RASSF6 by Western blot at 1 mug/mL.

Western Blot (WB) of anti-RASSF6 antibody

Western blot analysis of RASSF6 in 293 cell lysate with RASSF6 antibody at 1 μg/mL.
Rabbit Anti-RASSF6 Polyclonal Antibody – Cat# MBS150937

Other Notes

Small volumes of anti-RASSF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RASSF6 purchase

MBS150937 is an antibody targeting RASSF6. Also known as RASSF6 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RASSF6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras association domain-containing protein 6 isoform b
NCBI Official Synonym Full Names
Ras association (RalGDS/AF-6) domain family member 6
NCBI Official Symbol
RASSF6
UniProt Protein Name
Ras association domain-containing protein 6
UniProt Gene Name
RASSF6
UniProt Entry Name
RASF6_HUMAN
NCBI Protein Information
ras association domain-containing protein 6; putative RAS binding protein; Ras association (RalGDS/AF-6) domain family 6

NCBI Summary for RASSF6

This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
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UniProt Comments for RASSF6

RASSF6: Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 4q13.3

Molecular Function: protein binding

Biological Process: apoptosis; positive regulation of apoptosis; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-RASSF6 antibody

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