Rabbit Anti-RCBTB1 Polyclonal Antibody – Cat# MBS6341034

RCBTB1 Antibody – Rabbit Polyclonal

Name: RCBTB1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6341034
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6341034

This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RCBTB1, Polyclonal Antibody

Full Product Name

RCBTB1, ID (RCBTB1, CLLD7, E4.5, RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1) (MaxLight 650)

Product Gene Name

anti-RCBTB1 antibody

Product Synonym Names

RCBTB1; CLLD7; E4.5; RCC1 and BTB domain-containing protein 1; Chronic lymphocytic leukemia deletion region gene 7 protein; Regulator of chromosome condensation and BTB domain-containing protein 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

58,252 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (50106082..50159719, complement). Location: 13q14

OMIM

607867

3D Structure

ModBase 3D Structure for Q8NDN9

Immunogen

RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of human RCBTB1.

Conjugate

MaxLight650

Note

Preservative Free

Product Categories/Family for anti-RCBTB1 antibody

Antibodies; Cancer Markers; Leukemia

Applications Tested/Suitable for anti-RCBTB1 antibody

Western Blot (WB), FLISA

Application Notes for anti-RCBTB1 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RCBTB1 antibody

Genuneit, J., et al. Clin. Exp. Allergy 39(12):1875-1888(2009). Guo, D.F., et al. J. Biol. Chem. 279(20):21109-21120(2004). Dunham, A., et al. Nature 428(6982):522-528(2004). Solomou, E.E., et al. Leuk. Lymphoma 44(9):1579-1585(2003). Mabuchi, H., et al. Cancer Res. 61(7):2870-2877(2001).

Other Notes

Small volumes of anti-RCBTB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RCBTB1 purchase

MBS6341034 is an antibody targeting RCBTB1. Also known as RCBTB1, ID (RCBTB1, CLLD7, E4.5, RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1) (MaxLight 650). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RCBTB1. It may not necessarily be applicable to this product.

NCBI GI #

57242759

NCBI GeneID

55213

NCBI Accession #

NP_060661.3

UniProt Primary Accession #

Q8NDN9

UniProt Secondary Accession #

Q8IY29; Q969U9

UniProt Related Accession #

Q8NDN9

GenBank Nucleotide #

NM_018191.3

NCBI Official Full Name

RCC1 and BTB domain-containing protein 1

NCBI Official Synonym Full Names

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

NCBI Official Symbol

RCBTB1

NCBI Official Synonym Symbols

GLP; CLLD7; CLLL7; RP11-185C18.1

UniProt Protein Name

RCC1 and BTB domain-containing protein 1

UniProt Synonym Protein Names

Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; Regulator of chromosome condensation and BTB domain-containing protein 1

Protein Family

RCC1 and BTB domain-containing protein

UniProt Gene Name

RCBTB1

UniProt Synonym Gene Names

CLLD7; E4.5; CLL deletion region gene 7 protein

UniProt Entry Name

RCBT1_HUMAN

NCBI Protein Information

RCC1 and BTB domain-containing protein 1; CLL deletion region gene 7 protein; GDP/GTP exchange factor (GEF)-like protein; chronic lymphocytic leukemia deletion region gene 7 protein; regulator of chromosome condensation and BTB domain-containing protein 1

UniProt Comments for RCBTB1

RCBTB1: May be involved in cell cycle regulation by chromatin remodeling. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation; Cell cycle regulation

Chromosomal Location of Human Ortholog: 13q14

Cellular Component: cytoplasm; nucleus

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; chromatin modification; cell cycle

Disease: Alcohol Dependence

Research Articles on RCBTB1

1. Data show that the biological actions of Clld7 are consistent with those of a tumor suppressor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-RCBTB1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with RCBTB1 and Neoplasms
Cell Transformation, Neoplastic Antibodies	>1 publications with RCBTB1 and Cell Transformation, Neoplastic
Necrosis Antibodies	>1 publications with RCBTB1 and Necrosis

Organs/Tissues associated with anti-RCBTB1 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with RCBTB1 and Skin
Blood Antibodies	>1 publications with RCBTB1 and Blood