Rabbit Anti-RDX Polyclonal Antibody – Cat# MBS6341167

RDX Antibody – Rabbit Polyclonal

Name: RDX Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6341167
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6341167

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RDX, Polyclonal Antibody

Full Product Name

RDX, CT (RDX, Radixin) (MaxLight 750)

Product Gene Name

anti-RDX antibody

Product Synonym Names

RDX; Radixin

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

71,049 Da

OMIM

179410

3D Structure

ModBase 3D Structure for P35241

Immunogen

RDX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-495 amino acids from the C-terminal region of human RDX.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-RDX antibody

Antibodies; Actin Related Proteins

Applications Tested/Suitable for anti-RDX antibody

Western Blot (WB), FLISA

Application Notes for anti-RDX antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RDX antibody

Gloerich, M., et al. Mol. Cell. Biol. 30(22):5421-5431(2010). Kramer, B., et al. Eur. J. Immunol. 39(12):3447-3458(2009). Parisiadou, L., et al. J. Neurosci. 29(44):13971-13980(2009). Belkina, N.V., et al. Proc. Natl. Acad. Sci. U.S.A. 106(12):4707-4712(2009). Wolf, C., et al. BMC Med. Genet. 10, 91 (2009).

Other Notes

Small volumes of anti-RDX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RDX purchase

MBS6341167 is an antibody targeting RDX. Also known as RDX, CT (RDX, Radixin) (MaxLight 750). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RDX. It may not necessarily be applicable to this product.

NCBI GI #

4506467

NCBI GeneID

5962

NCBI Accession #

NP_002897.1

UniProt Primary Accession #

P35241

UniProt Secondary Accession #

Q86Y61; A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7

UniProt Related Accession #

P35241

GenBank Nucleotide #

NM_002906.3

NCBI Official Full Name

radixin isoform 2

NCBI Official Synonym Full Names

radixin

NCBI Official Symbol

RDX

NCBI Official Synonym Symbols

DFNB24

UniProt Protein Name

Radixin

Protein Family

Protein roadkill

UniProt Gene Name

RDX

UniProt Entry Name

RADI_HUMAN

NCBI Protein Information

radixin

NCBI Summary for RDX

Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

UniProt Comments for RDX

Radixin: a cytoskeletal protein of the ERM family which includes ezrin and moiesin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. May play a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: extracellular space; focal adhesion; T-tubule; ruffle; stereocilium; extrinsic to membrane; cytoskeleton; lamellipodium; apical part of cell; cytoplasm; plasma membrane; filopodium; cleavage furrow

Molecular Function: protein binding; actin binding

Biological Process: microvillus biogenesis; apical protein localization; actin filament capping

Disease: Deafness, Autosomal Recessive 24

Research Articles on RDX

1. These data suggest an association between RDX polymorphisms and the clinical features of RA patients, particularly the ESR

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RDX antibody

Reference Product	PubMed Publications
SLC9A3R2 antibody	>1 publications with RDX and SLC9A3R2
ROCK2 antibody	>1 publications with RDX and ROCK2

Pathways associated with anti-RDX antibody

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Diseases associated with anti-RDX antibody

Disease Name	Pubmed Publications
Poisoning Antibodies	>20 publications with RDX and Poisoning
Weight Loss Antibodies	>6 publications with RDX and Weight Loss
Liver Diseases Antibodies	>6 publications with RDX and Liver Diseases
Anemia Antibodies	>4 publications with RDX and Anemia
Liver Neoplasms Antibodies	>3 publications with RDX and Liver Neoplasms
Carcinoma Antibodies	>3 publications with RDX and Carcinoma
Hypertension Antibodies	>3 publications with RDX and Hypertension
Disease Models, Animal Antibodies	>3 publications with RDX and Disease Models, Animal
Carcinoma, Hepatocellular Antibodies	>2 publications with RDX and Carcinoma, Hepatocellular
Necrosis Antibodies	>2 publications with RDX and Necrosis

Organs/Tissues associated with anti-RDX antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>35 publications with RDX and Blood
Liver Antibodies	>29 publications with RDX and Liver
Brain Antibodies	>19 publications with RDX and Brain
Skin Antibodies	>11 publications with RDX and Skin
Kidney Antibodies	>9 publications with RDX and Kidney
Bone Antibodies	>9 publications with RDX and Bone
Lung Antibodies	>7 publications with RDX and Lung
Muscle Antibodies	>6 publications with RDX and Muscle
Heart Antibodies	>5 publications with RDX and Heart
Stomach Antibodies	>5 publications with RDX and Stomach