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RGS9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6009958

This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RGS9, Polyclonal Antibody
Full Product Name
RGS9, NT (RGS9, Regulator of G-protein signaling 9)
Product Gene Name
anti-RGS9 antibody
Product Synonym Names
Anti -RGS9, NT (RGS9, Regulator of G-protein signaling 9)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
76,966 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (63133456..63223821). Location: 17q24
OMIM
604067
3D Structure
ModBase 3D Structure for O75916
Immunogen
RGS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-178 amino acids from the N-terminal region of human RGS9.

Product Categories/Family for anti-RGS9 antibody

Antibodies; Abs to G Proteins
Applications Tested/Suitable for anti-RGS9 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RGS9 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-RGS9 antibody

RGS9 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RGS9 antibody detected the RGS9 protein (arrow).
Rabbit Anti-RGS9 Polyclonal Antibody – Cat# MBS6009958

Immunohistochemistry (IHC) of anti-RGS9 antibody

RGS9 Antibody (N-term) (AP14236a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RGS9 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-RGS9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6009958

Other Notes

Small volumes of anti-RGS9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RGS9 purchase

MBS6009958 is an antibody targeting RGS9. Also known as RGS9, NT (RGS9, Regulator of G-protein signaling 9). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RGS9. It may not necessarily be applicable to this product.

NCBI GI #
260099635
NCBI GeneID
8787
NCBI Accession #
NP_001159405.1
UniProt Primary Accession #
O75916
UniProt Secondary Accession #
O75573; Q696R2; Q8TD64; Q8TD65; Q9HC32; Q9HC33; A8K3C0
UniProt Related Accession #
O75916
GenBank Nucleotide #
NM_001165933.1
NCBI Official Full Name
regulator of G-protein signaling 9 isoform 3
NCBI Official Synonym Full Names
regulator of G-protein signaling 9
NCBI Official Symbol
RGS9
NCBI Official Synonym Symbols
PERRS; RGS9L
UniProt Protein Name
Regulator of G-protein signaling 9
Protein Family
Regulator of G-protein signaling
UniProt Gene Name
RGS9
UniProt Synonym Gene Names
RGS9
UniProt Entry Name
RGS9_HUMAN
NCBI Protein Information
regulator of G-protein signaling 9; regulator of G-protein signalling 9

UniProt Comments for RGS9

RGS9: belongs to the 'regulator of G protein signaling' family. Inhibits signal transduction by increasing the GTPAse activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction. Four alternatively spliced isoforms have been described.

Protein type: GAPs; GAPs, RGS

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: cytoplasm; plasma membrane; heterotrimeric G-protein complex; nucleus

Molecular Function: signal transducer activity; protein complex binding; GTPase activator activity

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; nervous system development; regulation of rhodopsin mediated signaling; visual perception; response to estrogen stimulus; dopamine receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity

Disease: Prolonged Electroretinal Response Suppression
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Research Articles on RGS9

1. These studies with humans, rats and mice implicate RGS9-2 as a factor in regulating body weight.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RGS9 antibody

 Reference Product  PubMed Publications
 GNB5 antibody  >24 publications with RGS9 and GNB5
 RGS9BP antibody  >12 publications with RGS9 and RGS9BP
 GNB1 antibody  >1 publications with RGS9 and GNB1
 GNGT1 antibody  >1 publications with RGS9 and GNGT1
 GNAT1 antibody  >1 publications with RGS9 and GNAT1

Pathways associated with anti-RGS9 antibody

 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway antibodies  Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram

Diseases associated with anti-RGS9 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >17 publications with RGS9 and Nervous System Diseases
 Substance-Related Disorders Antibodies  >13 publications with RGS9 and Substance-Related Disorders
 Mental Disorders Antibodies  >11 publications with RGS9 and Mental Disorders
 Movement Disorders Antibodies  >10 publications with RGS9 and Movement Disorders
 Brain Diseases Antibodies  >7 publications with RGS9 and Brain Diseases
 Dyskinesias Antibodies  >7 publications with RGS9 and Dyskinesias
 Schizophrenia Antibodies  >7 publications with RGS9 and Schizophrenia
 Dyskinesia, Drug-Induced Antibodies  >6 publications with RGS9 and Dyskinesia, Drug-Induced
 Kidney Diseases Antibodies  >1 publications with RGS9 and Kidney Diseases
 Seizures Antibodies  >1 publications with RGS9 and Seizures

Organs/Tissues associated with anti-RGS9 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >69 publications with RGS9 and Eye
 Brain Antibodies  >64 publications with RGS9 and Brain
 Nerve Antibodies  >7 publications with RGS9 and Nerve
 Kidney Antibodies  >3 publications with RGS9 and Kidney
 Blood Antibodies  >2 publications with RGS9 and Blood
 Lung Antibodies  >1 publications with RGS9 and Lung
 Muscle Antibodies  >1 publications with RGS9 and Muscle
 Embryonic Tissue Antibodies  >1 publications with RGS9 and Embryonic Tissue
 Vascular Antibodies  >1 publications with RGS9 and Vascular
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