Rabbit Anti-RNF135 Polyclonal Antibody – Cat# MBS6342585

RNF135 Antibody – Rabbit Polyclonal

Name: RNF135 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6342585
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6342585

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RNF135, Polyclonal Antibody

Full Product Name

RNF135, CT (RNF135, E3 ubiquitin-protein ligase RNF135, RIG-I E3 ubiquitin ligase, RING finger protein 135, Riplet) (MaxLight 650)

Product Gene Name

anti-RNF135 antibody

Product Synonym Names

RNF135; E3 ubiquitin-protein ligase RNF135; RIG-I E3 ubiquitin ligase; RING finger protein 135; Riplet

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

gene 614192

3D Structure

ModBase 3D Structure for Q8IUD6

Immunogen

RNF135 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human RNF135.

Conjugate

MaxLight650

Note

Preservative Free

Product Categories/Family for anti-RNF135 antibody

Antibodies; Ubiquitin Ligases

Applications Tested/Suitable for anti-RNF135 antibody

Western Blot (WB), FLISA

Application Notes for anti-RNF135 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RNF135 antibody

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010): You, F., et al. Nat. Immunol. 10(12):1300-1308(2009). Visser, R., et al. Am. J. Med. Genet. A 149A (4), 806-808 (2009): Oshiumi, H., et al. J. Biol. Chem. 284(2):807-817(2009). Gao, D., et al. PLoS ONE 4 (6), E5760 (2009).

Other Notes

Small volumes of anti-RNF135 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNF135 purchase

MBS6342585 is an antibody targeting RNF135. Also known as RNF135, CT (RNF135, E3 ubiquitin-protein ligase RNF135, RIG-I E3 ubiquitin ligase, RING finger protein 135, Riplet) (MaxLight 650). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RNF135. It may not necessarily be applicable to this product.

NCBI GI #

37655167

NCBI GeneID

84282

NCBI Accession #

NP_115698.3

UniProt Primary Accession #

Q8IUD6

UniProt Related Accession #

Q8IUD6

GenBank Nucleotide #

NP_115698.3

NCBI Official Full Name

E3 ubiquitin-protein ligase RNF135 isoform 1

NCBI Official Synonym Full Names

ring finger protein 135

NCBI Official Symbol

RNF135

NCBI Official Synonym Symbols

L13; MMFD; REUL; Riplet

UniProt Protein Name

E3 ubiquitin-protein ligase RNF135

UniProt Synonym Protein Names

RIG-I E3 ubiquitin ligase; REUL; RING finger protein 135; Riplet

Protein Family

E3 ubiquitin-protein ligase

UniProt Gene Name

RNF135

UniProt Synonym Gene Names

L13; REUL

UniProt Entry Name

RN135_HUMAN

NCBI Protein Information

E3 ubiquitin-protein ligase RNF135

NCBI Summary for RNF135

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Research Articles on RNF135

1. Riplet, and not TRIM25, is required endogenously for the ubiquitination of RIG-I.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.