Rabbit Anti-RNF6 Polyclonal Antibody – Cat# MBS6342962

RNF6 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RNF6 antibody detected the RNF6 protein (arrow).

RNF6 Antibody – Rabbit Polyclonal

Name: RNF6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6342962
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6342962

The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RNF6, Polyclonal Antibody

Full Product Name

RNF6, CT (RNF6, SPG2, E3 ubiquitin-protein ligase RNF6) (AP)

Product Gene Name

anti-RNF6 antibody

Product Synonym Names

RNF6; SPG2; E3 ubiquitin-protein ligase RNF6

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

133239

3D Structure

ModBase 3D Structure for Q9Y252

Immunogen

RNF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-558 amino acids from the C-terminal region of human RNF6.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-RNF6 antibody

Antibodies; Ubiquitin Ligases

Applications Tested/Suitable for anti-RNF6 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-RNF6 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RNF6 antibody

Xu, K., et al. Cancer Cell 15(4):270-282(2009). Zhu, L., et al. Sci. China, C, Life Sci. 51(4):302-307(2008). Tursun, B., et al. Genes Dev. 19(19):2307-2319(2005). Lo, H.S., et al. Cancer Res. 62(15):4191-4193(2002). Lopez, P., et al. Mol. Cell. Biol. 22(10):3488-3496(2002).

Other Notes

Small volumes of anti-RNF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNF6 purchase

MBS6342962 is an antibody targeting RNF6. Also known as RNF6, CT (RNF6, SPG2, E3 ubiquitin-protein ligase RNF6) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RNF6. It may not necessarily be applicable to this product.

NCBI GI #

34305295

NCBI GeneID

6049

NCBI Accession #

NP_898865.1

UniProt Primary Accession #

Q9Y252

UniProt Related Accession #

Q9Y252

GenBank Nucleotide #

NP_898865.1

NCBI Official Full Name

E3 ubiquitin-protein ligase RNF6 isoform 1

NCBI Official Synonym Full Names

ring finger protein 6

NCBI Official Symbol

RNF6

UniProt Protein Name

E3 ubiquitin-protein ligase RNF6

Protein Family

E3 ubiquitin-protein ligase

UniProt Gene Name

RNF6

UniProt Synonym Gene Names

SPG2

UniProt Entry Name

RNF6_HUMAN

NCBI Protein Information

E3 ubiquitin-protein ligase RNF6

Research Articles on RNF6

1. downregulation of miR-26a-5p plays essential roles in breast cancer by mediating RNF6/ERalpha/Bcl-xL axis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.