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RPAIN Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6006584

MBS6006584 is an antibody targeting RPAIN. Also known as RPAIN (RPA-interacting Protein, RIP, hRIP). Reactive in Human. Host: Mouse. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RPAIN, Polyclonal Antibody
Full Product Name
RPAIN (RPA-interacting Protein, RIP, hRIP)
Product Gene Name
Product Synonym Names
Anti -RPAIN (RPA-interacting Protein, RIP, hRIP)
Immunogen Sequence
MAESLRSPRR SLYKLVGSPP WKEAFRQRCL ERMRNSRDRL LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN ALQSVENCPE DLAQLEELID MAVLEEIQQE LIKQEQSIIS EYEKSLQFDE KCLSIMLAEW EANPLICPVC TKYNLRITSG VVVCQCGLSI PSHSSELTEQ KLRACLEGSI NEHSAHCPHT PEFSVTGGTE EKSSLLMSCL ACDTWAVIL
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human RPAIN.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
24,784 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (5322961..5336340). Location: 17p13.2
3D Structure
ModBase 3D Structure for Q86UA6
Immunogen
Full length human RPAIN, aa1-219 (NP_001028174.1).
Applications Tested/Suitable for anti-RPAIN antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-RPAIN antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-RPAIN antibody

RIP polyclonal antibody. Western Blot analysis of RIP expression in human placenta.
Mouse Anti-RPAIN Polyclonal Antibody – Cat# MBS6006584

Western Blot (WB) of anti-RPAIN antibody

Western Blot analysis of RPAIN expression in transfected 293T cell line by RPAIN polyclonal antibody. Lane 1: RIP transfected lysate (24.09kD). Lane 2: Non-transfected lysate.
Mouse Anti-RPAIN Polyclonal Antibody, Western Blot (WB) – Cat# MBS6006584

Immunofluorescence (IF) of anti-RPAIN antibody

Immunofluorescence of purified antibody to RIP on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-RPAIN Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6006584

Other Notes

Small volumes of anti-RPAIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RPAIN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
RPAIN protein
NCBI Official Synonym Full Names
RPA interacting protein
NCBI Official Symbol
RPAIN
NCBI Official Synonym Symbols
RIP; HRIP
UniProt Protein Name
RPA-interacting protein
UniProt Gene Name
RPAIN
UniProt Synonym Gene Names
RIP; hRIP
UniProt Entry Name
RIP_HUMAN
NCBI Protein Information
RPA-interacting protein; nuclear transporter; RAP interaction protein

UniProt Comments for RPAIN

RPAIN: Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA replication; DNA repair, damage

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: PML body; cytoplasm; nucleolus; nucleus

Molecular Function: metal ion binding; protein complex binding

Biological Process: protein import into nucleus; DNA repair; DNA-dependent DNA replication; response to UV; DNA recombination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-RPAIN antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >3 publications with RPAIN and Pain
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