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RPAP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9212416

MBS9212416 is an antibody targeting RPAP1. Also known as RPAP1 Antibody (N-term). Reactive in Human. Host: Rabbit. The function of this gene is unknown. [provided byRefSeq]. More details

$240 / 0.08 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RPAP1, Polyclonal Antibody
Full Product Name
RPAP1 Antibody (N-term)
Product Gene Name
anti-RPAP1 antibody
Product Synonym Names
RNA polymerase II-associated protein 1; RPAP1; KIAA1403
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.4 (lot specific)
Specificity
This RPAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the N-terminal region of human RPAP1.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
RPAP1 peptide (MBS9222298) is used for blocking the activity of RPAP1 antibody (MBS9212416)
Molecular Weight
152755
Immunogen Sequence Positions
282-310
OMIM
611475
3D Structure
ModBase 3D Structure for Q9BWH6
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Applications Tested/Suitable for anti-RPAP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-RPAP1 antibody
WB~~1:1000

Western Blot (WB) of anti-RPAP1 antibody

RPAP1 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RPAP1 antibody detected the RPAP1 protein (arrow).
Rabbit Anti-RPAP1 Polyclonal Antibody – Cat# MBS9212416

Product References and Citations for anti-RPAP1 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kuraoka, I., et al. DNA Repair (Amst.) 6(6):841-851(2007)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)

Other Notes

Small volumes of anti-RPAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RPAP1. It may not necessarily be applicable to this product.

NCBI GI #
24430139
NCBI GeneID
26015
NCBI Accession #
NP_056355.2
UniProt Primary Accession #
Q9BWH6
UniProt Secondary Accession #
Q9H9I2; Q9NSQ5; Q9P2E4; Q9UFS7
UniProt Related Accession #
Q9BWH6
GenBank Nucleotide #
NM_015540.3
NCBI Official Full Name
RNA polymerase II-associated protein 1
NCBI Official Synonym Full Names
RNA polymerase II associated protein 1
NCBI Official Symbol
RPAP1
UniProt Protein Name
RNA polymerase II-associated protein 1
Protein Family
RNA polymerase II-associated protein
UniProt Gene Name
RPAP1
UniProt Synonym Gene Names
KIAA1403
UniProt Entry Name
RPAP1_HUMAN
NCBI Protein Information
RNA polymerase II-associated protein 1

NCBI Summary for RPAP1

This protein forms part of the RNA polymerase II (RNAPII) enzyme complex and may recruit RNAPII to chromatin through its interaction with acetylated histones. [provided by RefSeq, Jul 2012]

UniProt Comments for RPAP1

RPAP1: Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. Required for interaction of the RNA polymerase II complex with acetylated histone H3. Belongs to the RPAP1 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: nucleus

Molecular Function: DNA binding; DNA-directed RNA polymerase activity

Biological Process: transcription from RNA polymerase II promoter
Show more

Research Articles on RPAP1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RPAP1 antibody

 Reference Product  PubMed Publications
 RPAP2 antibody  >1 publications with RPAP1 and RPAP2
 RPAP3 antibody  >1 publications with RPAP1 and RPAP3

Diseases associated with anti-RPAP1 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with RPAP1 and Breast Neoplasms
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