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RPS17 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3220730

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RPS17, Polyclonal Antibody
Full Product Name
RPS17 Antibody - N-terminal region
Product Gene Name
anti-RPS17 antibody
Product Synonym Gene Name
S17; DBA4; RPS17L; RPS17L1; RPS17L2
Immunogen Sequence
Synthetic peptide located within the following region: RTKTVKKAAR VIIEKYYTRL GNDFHTNKRV CEEIAIIPSK KLRNKIAGYV
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
RPS17 peptide (MBS3245532) is used for blocking the activity of RPS17 antibody (MBS3220730)
Molecular Weight
15 kDa
OMIM
gene 612527
3D Structure
ModBase 3D Structure for P08708
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RPS17

Product Categories/Family for anti-RPS17 antibody

Polyclonal; Disease Related; DNA/RNA/Protein Interactions
Applications Tested/Suitable for anti-RPS17 antibody
Western Blot (WB)

Western Blot (WB) of anti-RPS17 antibody

Host: Rabbit
Target Name: RPS17
Sample Tissue: Human THP-1 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-RPS17 Polyclonal Antibody – Cat# MBS3220730

Other Notes

Small volumes of anti-RPS17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPS17 purchase

MBS3220730 is an antibody targeting RPS17. Also known as RPS17 Antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RPS17. It may not necessarily be applicable to this product.

NCBI GI #
4506693
NCBI GeneID
6218
NCBI Accession #
NP_001012.1
UniProt Primary Accession #
P08708
UniProt Related Accession #
P08708
GenBank Nucleotide #
NM_001021.4 
NCBI Official Full Name
40S ribosomal protein S17
NCBI Official Synonym Full Names
ribosomal protein S17
NCBI Official Symbol
RPS17
NCBI Official Synonym Symbols
S17; DBA4; RPS17L; RPS17L1; RPS17L2
UniProt Protein Name
40S ribosomal protein S17
Protein Family
40S ribosomal protein
UniProt Gene Name
RPS17
UniProt Entry Name
RS17_HUMAN
NCBI Protein Information
40S ribosomal protein S17

UniProt Comments for RPS17

RPS17: Defects in RPS17 are the cause of Diamond-Blackfan anemia type 4 (DBA4). DBA4 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Belongs to the ribosomal protein S17e family.

Protein type: Ribosomal; Translation

Chromosomal Location of Human Ortholog: 15q

Cellular Component: focal adhesion; membrane; ribosome; cytosol

Molecular Function: structural constituent of ribosome

Biological Process: SRP-dependent cotranslational protein targeting to membrane; viral reproduction; translation; viral infectious cycle; translational termination; ribosomal small subunit biogenesis and assembly; erythrocyte homeostasis; translational elongation; cellular protein metabolic process; mRNA catabolic process, nonsense-mediated decay; translational initiation; ribosomal small subunit assembly and maintenance; gene expression; viral transcription; rRNA processing

Disease: Diamond-blackfan Anemia 4
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Research Articles on RPS17

1. Nuclear and nucleolar localization signals within the human ribosomal protein S17 have been mapped.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RPS17 antibody

 Reference Product  PubMed Publications
 RPS19 antibody  >28 publications with RPS17 and RPS19
 RPS24 antibody  >24 publications with RPS17 and RPS24
 RPL35A antibody  >22 publications with RPS17 and RPL35A
 RPL11 antibody  >19 publications with RPS17 and RPL11
 RPS7 antibody  >11 publications with RPS17 and RPS7
 RPS14 antibody  >5 publications with RPS17 and RPS14
 RPS8 antibody  >3 publications with RPS17 and RPS8
 RPS29 antibody  >2 publications with RPS17 and RPS29
 RPS20 antibody  >1 publications with RPS17 and RPS20

Pathways associated with anti-RPS17 antibody

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram

Diseases associated with anti-RPS17 antibody

 Disease Name  Pubmed Publications
 Anemia, Diamond-Blackfan Antibodies  >26 publications with RPS17 and Anemia, Diamond-Blackfan
 Diamond-Blackfan Anemia 4 Antibodies  >6 publications with RPS17 and Diamond-Blackfan Anemia 4
 Abnormalities, Multiple Antibodies  >4 publications with RPS17 and Abnormalities, Multiple
 Aneuploidy Antibodies  >2 publications with RPS17 and Aneuploidy
 Carcinoma Antibodies  >1 publications with RPS17 and Carcinoma
 Cognition Disorders Antibodies  >1 publications with RPS17 and Cognition Disorders
 Fatty Liver Antibodies  >1 publications with RPS17 and Fatty Liver
 Disorders of Sex Development Antibodies  >1 publications with RPS17 and Disorders of Sex Development
 Liver Neoplasms Antibodies  >1 publications with RPS17 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with RPS17 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-RPS17 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with RPS17 and Blood
 Bone Marrow Antibodies  >11 publications with RPS17 and Bone Marrow
 Bone Antibodies  >11 publications with RPS17 and Bone
 Heart Antibodies  >4 publications with RPS17 and Heart
 Liver Antibodies  >3 publications with RPS17 and Liver
 Brain Antibodies  >2 publications with RPS17 and Brain
 Intestine Antibodies  >1 publications with RPS17 and Intestine
 Kidney Antibodies  >1 publications with RPS17 and Kidney
 Muscle Antibodies  >1 publications with RPS17 and Muscle
 Eye Antibodies  >1 publications with RPS17 and Eye
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