Rabbit Anti-RRAS Polyclonal Antibody – Cat# MBS7134375

IHC image of MBS7134375 diluted at 1:100 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

RRAS Antibody – Rabbit Polyclonal

Name: RRAS Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS7134375
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7134375

MBS7134375 is an antibody targeting RRAS. Also known as RRAS Antibody. Reactive in Human. Host: Rabbit. More details

$230 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RRAS, Polyclonal Antibody

Full Product Name

RRAS Antibody

Product Gene Name

anti-RRAS antibody

Product Synonym Names

Ras-related protein R-Ras (p23); RRAS

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Purity/Purification

Antigen Affinity Purified

Preparation and Storage

Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: RRAS (MBS7134375)
HRP Conjugated Antibody: RRAS (MBS7134376)

Matching Pairs

Unconjugated Antibody: RRAS (MBS7134375)
FITC Conjugated Antibody: RRAS (MBS7134377)

Molecular Weight

23,480 Da

OMIM

165090

3D Structure

ModBase 3D Structure for P10301

Immunogen

Peptide sequence from Human Ras-related protein R-Ras protein (7-23AA)

Immunogen Species

Human

Conjugate

Non-conjugated

Product Categories/Family for anti-RRAS antibody

Cell Biology

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-RRAS antibody

ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-RRAS antibody

IHC: 1:20-1:200

Other Notes

Small volumes of anti-RRAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RRAS. It may not necessarily be applicable to this product.

NCBI GI #

5454028

NCBI GeneID

6237

NCBI Accession #

NP_006261.1

UniProt Primary Accession #

P10301

UniProt Secondary Accession #

Q6FH12

UniProt Related Accession #

P10301

GenBank Nucleotide #

NM_006270.3

NCBI Official Full Name

ras-related protein R-Ras

NCBI Official Synonym Full Names

related RAS viral (r-ras) oncogene homolog

NCBI Official Symbol

RRAS

UniProt Protein Name

Ras-related protein R-Ras

UniProt Synonym Protein Names

p23

Protein Family

Ras-related protein

UniProt Gene Name

RRAS

UniProt Entry Name

RRAS_HUMAN

NCBI Protein Information

ras-related protein R-Ras; Oncogene RRAS; p23

NCBI Summary for RRAS

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

UniProt Comments for RRAS

RRas: a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K.

Protein type: G protein, monomeric, Ras; G protein; Motility/polarity/chemotaxis; G protein, monomeric

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: focal adhesion; plasma membrane

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein complex binding

Biological Process: axon guidance; synaptic transmission; positive regulation of angiogenesis; metabolic process; Ras protein signal transduction; leukocyte differentiation; regulation of protein kinase B signaling cascade; negative regulation of cell migration

Research Articles on RRAS

1. Contradicting the positive association reported in previous studies, our results indicate that R-Ras activation may negatively regulate the transformation of breast epithelial cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RRAS antibody

Reference Product	PubMed Publications
SRC antibody	>5 publications with RRAS and SRC
SEMA4D antibody	>3 publications with RRAS and SEMA4D
RAF1 antibody	>3 publications with RRAS and RAF1
EPHB2 antibody	>1 publications with RRAS and EPHB2

Pathways associated with anti-RRAS antibody

Products by Pathway	Pathway Diagram
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies	Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
CREB Phosphorylation Through The Activation Of Ras Pathway antibodies	CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
EPHB Forward Signaling Pathway antibodies	EPHB Forward Signaling Pathway Diagram
G Protein Signaling Pathways antibodies	G Protein Signaling Pathways Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Integrated Breast Cancer Pathway antibodies	Integrated Breast Cancer Pathway Diagram
MAPK Cascade Pathway antibodies	MAPK Cascade Pathway Diagram

Diseases associated with anti-RRAS antibody

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>11 publications with RRAS and Cell Transformation, Neoplastic
Nervous System Diseases Antibodies	>7 publications with RRAS and Nervous System Diseases
Breast Neoplasms Antibodies	>6 publications with RRAS and Breast Neoplasms
Brain Diseases Antibodies	>6 publications with RRAS and Brain Diseases
Inflammation Antibodies	>5 publications with RRAS and Inflammation
Neoplasm Metastasis Antibodies	>4 publications with RRAS and Neoplasm Metastasis
Neoplasms, Experimental Antibodies	>3 publications with RRAS and Neoplasms, Experimental
Liver Neoplasms Antibodies	>2 publications with RRAS and Liver Neoplasms
Uterine Cervical Neoplasms Antibodies	>2 publications with RRAS and Uterine Cervical Neoplasms
Fibrosis Antibodies	>2 publications with RRAS and Fibrosis

Organs/Tissues associated with anti-RRAS antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>15 publications with RRAS and Brain
Muscle Antibodies	>9 publications with RRAS and Muscle
Testis Antibodies	>7 publications with RRAS and Testis
Bone Antibodies	>7 publications with RRAS and Bone
Heart Antibodies	>6 publications with RRAS and Heart
Connective Tissue Antibodies	>4 publications with RRAS and Connective Tissue
Embryonic Tissue Antibodies	>4 publications with RRAS and Embryonic Tissue
Prostate Antibodies	>4 publications with RRAS and Prostate
Lymph Antibodies	>3 publications with RRAS and Lymph
Kidney Antibodies	>3 publications with RRAS and Kidney