Rabbit Anti-RSK2 Polyclonal Antibody – Cat# MBS6498284

RSK2 Antibody – Rabbit Polyclonal

Name: RSK2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6498284
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6498284

MBS6498284 is an antibody targeting RSK2. Also known as RSK2, Phosphorylated (Ser369) (Ribosomal S6 Kinase 2, RSK2, RSK-2, p90-RSK2, pp90RSK2, 90kD Ribosomal Protein S6 Kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated Protein Kinase 1, ISPK1, ISPK-1, MAP… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RSK2, Polyclonal Antibody

Full Product Name

RSK2, Phosphorylated (Ser369) (Ribosomal S6 Kinase 2, RSK2, RSK-2, p90-RSK2, pp90RSK2, 90kD Ribosomal Protein S6 Kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated Protein Kinase 1, ISPK1, ISPK-1, MAP Kinase-activated Protein Kinase 1b, MAPK-activated Prote

Product Gene Name

anti-RSK2 antibody

Product Synonym Names

Ribosomal Protein S6 Kinase 90kDa Polypeptide 3; CLS; EC=2.7.11.1; HU-3; MRX19; RSK

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Immunoaffinity chromatography.

Specificity

Recognizes human RPS6KA3 when phosphorylated at Ser369.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

83,736 Da

OMIM

300075

3D Structure

ModBase 3D Structure for P51812

Immunogen

Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser369 of human RPS6KA3 (KLH).

Conjugate

MaxLight750

Antigen Modification

Phosphorylated

Note

Preservative Free

Product Categories/Family for anti-RSK2 antibody

Antibodies; Protein Kinases; Ribosomal

Applications Tested/Suitable for anti-RSK2 antibody

FLISA, Dot Blot (DB)

Application Notes for anti-RSK2 antibody

FLISA: 1:1,000
Dot Blot: 1:500
Applications are based on unconjugated antibody.

Product References and Citations for anti-RSK2 antibody

1. Yang, X., et al., Cell 117(3):387-398 (2004). 2. Guimiot, F., et al., Gene Expr. Patterns 4(1):111-114 (2004). 3. Zeniou, M., et al., (er) Nucleic Acids Res. 32(3):1214-1223 (2004). 4. Vaidyanathan, H., et al., J. Biol. Chem. 278(34):32367-32372 (2003). 5. Zhang, Y., et al., J. Biol. Chem. 278(15):12650-12659 (2003).

Other Notes

Small volumes of anti-RSK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RSK2. It may not necessarily be applicable to this product.

NCBI GI #

4759050

NCBI GeneID

6197

NCBI Accession #

NP_004577

UniProt Primary Accession #

P51812

UniProt Secondary Accession #

Q4VAP3; Q59H26; Q5JPK8; Q7Z3Z7; B2R9V4

UniProt Related Accession #

P51812

GenBank Nucleotide #

NM_004586.2

NCBI Official Full Name

ribosomal protein S6 kinase alpha-3

NCBI Official Synonym Full Names

ribosomal protein S6 kinase, 90kDa, polypeptide 3

NCBI Official Symbol

RPS6KA3

NCBI Official Synonym Symbols

CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3

UniProt Protein Name

Ribosomal protein S6 kinase alpha-3

UniProt Synonym Protein Names

90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2

UniProt Gene Name

RPS6KA3

UniProt Synonym Gene Names

ISPK1; MAPKAPK1B; RSK2; S6K-alpha-3; p90-RSK 3; p90RSK3; ISPK-1; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; RSK-2

UniProt Entry Name

KS6A3_HUMAN

NCBI Protein Information

ribosomal protein S6 kinase alpha-3

NCBI Summary for RSK2

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]

Research Articles on RSK2

1. RPS6KA3 in three unrelated Coffin-Lowry syndrome patients including one from the historical Coffin-Lowry syndrome family and found two novel mutations, were analyzed.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RSK2 antibody

Reference Product	PubMed Publications
MAPK1 antibody	>2 publications with RSK2 and MAPK1
ELK1 antibody	>1 publications with RSK2 and ELK1
MAPK3 antibody	>1 publications with RSK2 and MAPK3

Pathways associated with anti-RSK2 antibody

Products by Pathway	Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies	Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
CREB Phosphorylation Pathway antibodies	CREB Phosphorylation Pathway Diagram
CREB Phosphorylation Through The Activation Of Ras Pathway antibodies	CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
Cellular Senescence Pathway antibodies	Cellular Senescence Pathway Diagram
Cellular Responses To Stress Pathway antibodies	Cellular Responses To Stress Pathway Diagram
Coregulation Of Androgen Receptor Activity Pathway antibodies	Coregulation Of Androgen Receptor Activity Pathway Diagram
Cytoplasmic Ribosomal Proteins Pathway antibodies	Cytoplasmic Ribosomal Proteins Pathway Diagram

Diseases associated with anti-RSK2 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>27 publications with RSK2 and Nervous System Diseases
Coffin-Lowry Syndrome Antibodies	>23 publications with RSK2 and Coffin-Lowry Syndrome
Disease Models, Animal Antibodies	>5 publications with RSK2 and Disease Models, Animal
Congenital Abnormalities Antibodies	>5 publications with RSK2 and Congenital Abnormalities
Brain Diseases Antibodies	>2 publications with RSK2 and Brain Diseases
Nervous System Malformations Antibodies	>2 publications with RSK2 and Nervous System Malformations
Carcinoma, Hepatocellular Antibodies	>2 publications with RSK2 and Carcinoma, Hepatocellular
Neural Tube Defects Antibodies	>1 publications with RSK2 and Neural Tube Defects
Liver Diseases Antibodies	>1 publications with RSK2 and Liver Diseases
Learning Disorders Antibodies	>1 publications with RSK2 and Learning Disorders

Organs/Tissues associated with anti-RSK2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>9 publications with RSK2 and Brain
Bone Antibodies	>3 publications with RSK2 and Bone
Embryonic Tissue Antibodies	>2 publications with RSK2 and Embryonic Tissue
Liver Antibodies	>2 publications with RSK2 and Liver
Ovary Antibodies	>1 publications with RSK2 and Ovary
Connective Tissue Antibodies	>1 publications with RSK2 and Connective Tissue
Testis Antibodies	>1 publications with RSK2 and Testis
Bone Marrow Antibodies	>1 publications with RSK2 and Bone Marrow
Kidney Antibodies	>1 publications with RSK2 and Kidney
Muscle Antibodies	>1 publications with RSK2 and Muscle