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S39A8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6344776

S39A8 encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
S39A8, Polyclonal Antibody
Full Product Name
S39A8, ID (SLC39A8, BIGM103, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6, Solute carrier family 39 member 8, Zrt-and Irt-like protein 8) (PE)
Product Gene Name
Product Synonym Gene Name
SLC39A8
Product Synonym Names
SLC39A8; BIGM103; ZIP8; Zinc transporter ZIP8; BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; Solute carrier family 39 member 8; Zrt-and Irt-like protein 8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human S39A8.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
48,089 Da
OMIM
608732
3D Structure
ModBase 3D Structure for Q9C0K1
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 218-246 in the central region of human S39A8.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-S39A8 antibody

Applications Tested/Suitable for anti-S39A8 antibody
Western Blot (WB), Flow Cytometry (FC/FACS), FLISA
Application Notes for anti-S39A8 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-S39A8 antibody

Western Blot analysis in CEM cell line lysates (35ug/lane), usingMBS6005119. S39A8 (arrow) was detected usingMBS6005119.
Rabbit Anti-S39A8 Polyclonal Antibody – Cat# MBS6344776

Flow Cytometry (FC/FACS) of anti-S39A8 antibody

Flow Cytometric analysis of CEM cells using MBS6005119 (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-S39A8 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6344776

Product References and Citations for anti-S39A8 antibody

1. Wang, L. Cancer Epidemiol. Biomarkers Prev. 17 (12), 3558-3566 (2008). 2. Aiba, I. Mol. Pharmacol. 74 (3), 823-833 (2008). 3. Besecker, B. Am. J. Physiol. Lung Cell Mol. Physiol. 294 (6), L1127-L1136 (2008).

Other Notes

Small volumes of anti-S39A8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S39A8 purchase

MBS6344776 is an antibody targeting S39A8. Also known as S39A8, ID (SLC39A8, BIGM103, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6, Solute carrier family 39 member 8, Zrt-and Irt-like protein 8) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for S39A8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc transporter ZIP8 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 8
NCBI Official Symbol
SLC39A8
NCBI Official Synonym Symbols
ZIP8; PP3105; BIGM103; LZT-Hs6
UniProt Protein Name
Zinc transporter ZIP8
UniProt Synonym Protein Names
BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; LZT-Hs6; Solute carrier family 39 member 8; Zrt- and Irt-like protein 8; ZIP-8
UniProt Gene Name
SLC39A8
UniProt Synonym Gene Names
BIGM103; ZIP8; LZT-Hs6; ZIP-8
UniProt Entry Name
S39A8_HUMAN
NCBI Protein Information
zinc transporter ZIP8; ZIP-8; Zrt- and Irt-like protein 8; solute carrier family 39 member 8; LIV-1 subfamily of ZIP zinc transporter 6; BCG induced integral membrane protein BIGM103; solute carrier family 39 (metal ion transporter), member 8; BCG-induced

NCBI Summary for S39A8

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]
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UniProt Comments for S39A8

SLC39A8: Acts as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, SLC family; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 4q24

Cellular Component: plasma membrane; integral to membrane

Molecular Function: metal ion transmembrane transporter activity

Biological Process: zinc ion transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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