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SAMD4A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8591230

Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug… More details

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Product Overview

Online Datasheet in PDF
Product Name
SAMD4A, Polyclonal Antibody
Full Product Name
SAMD4A Antibody
Product Gene Name
Product Synonym Names
SMG; SMGA; SAMD4; SMAUG; SMAUG1
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen affinity purification.
Specificity
The antibody detects endogenous levels of total SAMD4A protein.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
79,415 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (55033815..55260033). Location: 14q22.2
OMIM
610747
3D Structure
ModBase 3D Structure for Q9UPU9
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human sterile alpha motif domain containing 4A

Product Categories/Family for anti-SAMD4A antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SAMD4A antibody
Immunohistochemistry (IHC)
Application Notes for anti-SAMD4A antibody
IHC: 1:25-1:100

Other Notes

Small volumes of anti-SAMD4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAMD4A purchase

MBS8591230 is an antibody targeting SAMD4A. Also known as SAMD4A Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SAMD4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SAMD4A protein
NCBI Official Synonym Full Names
sterile alpha motif domain containing 4A
NCBI Official Symbol
SAMD4A
NCBI Official Synonym Symbols
SMG; SMGA; SAMD4; SMAUG; SMAUG1
UniProt Protein Name
Protein Smaug homolog 1
UniProt Synonym Protein Names
Sterile alpha motif domain-containing protein 4A
Protein Family
UniProt Gene Name
SAMD4A
UniProt Synonym Gene Names
KIAA1053; SAMD4; SMAUG1; Smaug 1; hSmaug1
UniProt Entry Name
SMAG1_HUMAN
NCBI Protein Information
protein Smaug homolog 1; SAM domain-containing protein 4A

NCBI Summary for SAMD4A

Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]
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UniProt Comments for SAMD4A

Function: Acts as a translational repressor of SRE-containing messengers. Ref.6

Subcellular location: Cytoplasm. Cell projection › dendrite

By similarity. Cell junction › synapse › synaptosome

By similarity. Note: Enriched in synaptoneurosomes

By similarity. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Ref.6

Sequence similarities: Belongs to the SMAUG family.Contains 1 SAM (sterile alpha motif) domain.

Sequence caution: The sequence AAH57838.1 differs from that shown. Reason: Intron retention.The sequence AAP97302.1 differs from that shown. Reason: Intron retention.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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