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SAMHD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9232186

Description: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)Background: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of… More details

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Product Overview

Product Name
SAMHD1, Polyclonal Antibody
Full Product Name
SAMHD1 Antibody (Center)
Product Gene Name
Product Synonym Names
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; 315-; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1; SAMHD1; MOP5
Clonality
Polyclonal
Isotype
Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This SAMHD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-230 amino acids from the Central region of human SAMHD1.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
72201
OMIM
phenotype 614415
3D Structure
ModBase 3D Structure for Q9Y3Z3
Antigen Source
Human
Antigen Region
204-230
Antigen Type
Synthesized Peptide

Product Categories/Family for anti-SAMHD1 antibody

Applications Tested/Suitable for anti-SAMHD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SAMHD1 antibody
WB: 0.25

Western Blot (WB) of anti-SAMHD1 antibody

All lanes : Anti-SAMHD1 Antibody (Center) at 1:2000 dilution
Lane 1: THP-1 whole cell lysate
Lane 2: Ramos whole cell lysate
Lane 3: HepG2 whole cell lysate

Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 72 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Rabbit Anti-SAMHD1 Polyclonal Antibody – Cat# MBS9232186

Product References and Citations for anti-SAMHD1 antibody

Tomkova, H., et al. Eur J Dermatol 20(3):411-413(2010). Dale, R.C., et al. Am. J. Med. Genet. A 152A (4), 938-942 (2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Rice, G.I., et al. Nat. Genet. 41(7):829-832(2009). Liao, W., et al. Proteomics 8(13):2640-2650(2008).

Other Notes

Small volumes of anti-SAMHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAMHD1 purchase

MBS9232186 is an antibody targeting SAMHD1. Also known as SAMHD1 Antibody (Center). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SAMHD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform 1
NCBI Official Synonym Full Names
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
NCBI Official Symbol
SAMHD1
NCBI Official Synonym Symbols
DCIP; CHBL2; HDDC1; MOP-5; SBBI88; hSAMHD1
UniProt Protein Name
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Synonym Protein Names
Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1
UniProt Gene Name
SAMHD1
UniProt Synonym Gene Names
MOP5; dNTPase; DCIP; MOP-5
UniProt Entry Name
SAMH1_HUMAN
NCBI Protein Information
deoxynucleoside triphosphate triphosphohydrolase SAMHD1

NCBI Summary for SAMHD1

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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