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SARNP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6345042

This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SARNP, Polyclonal Antibody
Full Product Name
SARNP, ID (SARNP, HCC1, SAP domain-containing ribonucleoprotein, Cytokine-induced protein of 29kD, Nuclear protein Hcc-1, Proliferation-associated cytokine-inducible protein CIP29) (APC)
Product Gene Name
anti-SARNP antibody
Product Synonym Names
SARNP; HCC1; SAP domain-containing ribonucleoprotein; Cytokine-induced protein of 29kD; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
23,671 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (56146247..56211540, complement). Location: 12q13.2
OMIM
610049
3D Structure
ModBase 3D Structure for P82979
Immunogen
SARNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the Central region of human SARNP.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-SARNP antibody

Antibodies; Nuclear Proteins
Applications Tested/Suitable for anti-SARNP antibody
Western Blot (WB), FLISA
Application Notes for anti-SARNP antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SARNP antibody

SARNP Antibody (Center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the SARNP antibody detected the SARNP protein (arrow).
Rabbit Anti-SARNP Polyclonal Antibody – Cat# MBS6345042

Product References and Citations for anti-SARNP antibody

Sugiura, T., et al. Exp. Cell Res. 313(4):782-790(2007). Leaw, C.L., et al. Cell. Mol. Life Sci. 61(17):2264-2273(2004). Hashii, Y., et al. Leukemia 18(9):1546-1548(2004). Fukuda, S., et al. Biochem. Biophys. Res. Commun. 292(3):593-600(2002). Choong, M.L., et al. FEBS Lett. 496 (2-3), 109-116 (2001).

Other Notes

Small volumes of anti-SARNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SARNP purchase

MBS6345042 is an antibody targeting SARNP. Also known as SARNP, ID (SARNP, HCC1, SAP domain-containing ribonucleoprotein, Cytokine-induced protein of 29kD, Nuclear protein Hcc-1, Proliferation-associated cytokine-inducible protein CIP29) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SARNP. It may not necessarily be applicable to this product.

NCBI GI #
32129199
NCBI GeneID
84324
NCBI Accession #
NP_149073.1
UniProt Primary Accession #
P82979
UniProt Secondary Accession #
Q9P066; A8K393
UniProt Related Accession #
P82979
GenBank Nucleotide #
NM_033082.3
NCBI Official Full Name
SAP domain-containing ribonucleoprotein
NCBI Official Synonym Full Names
SAP domain containing ribonucleoprotein
NCBI Official Symbol
SARNP
NCBI Official Synonym Symbols
HCC1; THO1; CIP29; HSPC316
UniProt Protein Name
SAP domain-containing ribonucleoprotein
UniProt Synonym Protein Names
Cytokine-induced protein of 29 kDa; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29
Protein Family
SAP domain-containing ribonucleoprotein
UniProt Gene Name
SARNP
UniProt Synonym Gene Names
HCC1
UniProt Entry Name
SARNP_HUMAN
NCBI Protein Information
SAP domain-containing ribonucleoprotein; nuclear protein Hcc-1; hepatocellular carcinoma 1; cytokine induced protein 29 kDa; cytokine-induced protein of 29 kDa; proliferation associated cytokine-inducible protein CIP29; proliferation-associated cytokine-i

NCBI Summary for SARNP

This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
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UniProt Comments for SARNP

CIP29: Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single- stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nuclear speck; nucleus

Molecular Function: DNA binding

Biological Process: regulation of translation; mRNA export from nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Research Articles on SARNP

1. CIP29 physically and functionally associates with DDX39, suggesting their cooperation in the RNA metabolism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SARNP antibody

 Reference Product  PubMed Publications
 FUS antibody  >1 publications with SARNP and FUS
 DDX39 antibody  >1 publications with SARNP and DDX39

Diseases associated with anti-SARNP antibody

 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >2 publications with SARNP and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with SARNP and Liver Diseases
 Adenocarcinoma Antibodies  >2 publications with SARNP and Adenocarcinoma
 Endocrine System Diseases Antibodies  >1 publications with SARNP and Endocrine System Diseases

Organs/Tissues associated with anti-SARNP antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with SARNP and Liver
 Lung Antibodies  >1 publications with SARNP and Lung
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