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SARNP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9133729
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This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SARNP, Polyclonal Antibody
Full Product Name
SARNP Polyclonal Antibody
Product Gene Name
anti-SARNP antibody
Product Synonym Names
CIP29; HCC1; HSPC316; THO1
Immunogen Sequence
MATETVELHK LKLAELKQEC LARGLETKGI KQDLIHRLQA YLEEHAEEEA NEEDVLGDET EEEETKPIEL PVKEEEPPEK TVDVAAEKKV VKITSEIPQT ERMQKRAERF NVPVSLESKK AARAARFGIS SVPTKGLSSD NKPMVNLDKL KERAQRFGLN VSSISRKSED DEKLKKRKER FGIVTSSAGT GTTEDTEAKK RKRAERFGIA
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
Calculated: 23kDa
Observed: 29kDa
OMIM
AJ409089 Genomic DNA
3D Structure
ModBase 3D Structure for P82979
Immunogen
Recombinant protein of human SARNP
Immunogen Species
Human
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Nucleus, Nucleus speckle
Positive Samples
293T, HepG2, BxPC3, U-87MG, MCF-7

Product Categories/Family for anti-SARNP antibody

Polyclonal Antibodies
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SARNP antibody
Western Blot (WB)
Application Notes for anti-SARNP antibody
WB: 1:500 - 1:2000

Western Blot (WB) of anti-SARNP antibody

Western blot analysis of extracts of various cell lines, using SARNP antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Rabbit Anti-SARNP Polyclonal Antibody – Cat# MBS9133729

Other Notes

Small volumes of anti-SARNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SARNP purchase

MBS9133729 is an antibody targeting SARNP. Also known as SARNP Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SARNP. It may not necessarily be applicable to this product.

NCBI GI #
32129199
NCBI GeneID
84324
NCBI Accession #
NP_149073.1
UniProt Primary Accession #
P82979
UniProt Secondary Accession #
Q9P066; A8K393
UniProt Related Accession #
P82979
GenBank Nucleotide #
NM_033082.3
NCBI Official Full Name
SAP domain-containing ribonucleoprotein
NCBI Official Synonym Full Names
SAP domain containing ribonucleoprotein
NCBI Official Symbol
SARNP
NCBI Official Synonym Symbols
HCC1; THO1; CIP29; HSPC316
UniProt Protein Name
SAP domain-containing ribonucleoprotein
UniProt Synonym Protein Names
Cytokine-induced protein of 29 kDa; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29
Protein Family
SAP domain-containing ribonucleoprotein
UniProt Gene Name
SARNP
UniProt Synonym Gene Names
HCC1
NCBI Protein Information
SAP domain-containing ribonucleoprotein

UniProt Comments for SARNP

Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
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Research Articles on SARNP

1. Herein, the authors extend their previous research and provide evidence that ORF57 of human herpesvirus-8 interacts with CHTOP and CIP29, in contrast to POLDIP3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SARNP antibody

 Reference Product  PubMed Publications
 FUS antibody  >1 publications with SARNP and FUS
 DDX39 antibody  >1 publications with SARNP and DDX39

Diseases associated with anti-SARNP antibody

 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >2 publications with SARNP and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with SARNP and Liver Diseases
 Adenocarcinoma Antibodies  >2 publications with SARNP and Adenocarcinoma
 Endocrine System Diseases Antibodies  >1 publications with SARNP and Endocrine System Diseases

Organs/Tissues associated with anti-SARNP antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with SARNP and Liver
 Lung Antibodies  >1 publications with SARNP and Lung
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