Rabbit Anti-SEMG1 Polyclonal Antibody – Cat# MBS6346052

SEMG1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SEMG1 antibody detected the SEMG1 protein (arrow).

SEMG1 Antibody – Rabbit Polyclonal

Name: SEMG1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6346052
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6346052

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SEMG1, Polyclonal Antibody

Full Product Name

SEMG1, NT (SEMG1, SEMG, Semenogelin-1, Semenogelin I, Alpha-inhibin-92, Alpha-inhibin-31, Seminal basic protein) (PE)

Product Gene Name

anti-SEMG1 antibody

Product Synonym Names

SEMG1; SEMG; Semenogelin-1; Semenogelin I; Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

45,322 Da

OMIM

182140

3D Structure

ModBase 3D Structure for P04279

Immunogen

SEMG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-121 amino acids from the N-terminal region of human SEMG1.

Conjugate

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-SEMG1 antibody

Antibodies; Spermatogenesis; Testis Proteins

Applications Tested/Suitable for anti-SEMG1 antibody

Western Blot (WB), FLISA

Application Notes for anti-SEMG1 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SEMG1 antibody

Mitra, A., et al. Biol. Reprod. 82(3):489-496(2010). Yoshida, K., et al. Cell Motil. Cytoskeleton 66(2):99-108(2009). Ahmed, S.U., et al. Cytotherapy 11(2):238-244(2009). Edstrom, A.M., et al. J. Immunol. 181(5):3413-3421(2008). Emami, N., et al. J. Biol. Chem. 283(28):19561-19569(2008).

Other Notes

Small volumes of anti-SEMG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEMG1 purchase

MBS6346052 is an antibody targeting SEMG1. Also known as SEMG1, NT (SEMG1, SEMG, Semenogelin-1, Semenogelin I, Alpha-inhibin-92, Alpha-inhibin-31, Seminal basic protein) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEMG1. It may not necessarily be applicable to this product.

NCBI GI #

4506883

NCBI GeneID

6406

NCBI Accession #

NP_002998.1

UniProt Primary Accession #

P04279

UniProt Secondary Accession #

Q53ZV0; Q53ZV1; Q53ZV2; Q6X4I9; Q6Y809; Q6Y822; Q6Y823; Q86U64; Q96QM3

UniProt Related Accession #

P04279

GenBank Nucleotide #

NM_003007.3

NCBI Official Full Name

semenogelin-1 preproprotein

NCBI Official Synonym Full Names

semenogelin I

NCBI Official Symbol

SEMG1

NCBI Official Synonym Symbols

SGI; SEMG; CT103; dJ172H20.2

UniProt Protein Name

Semenogelin-1

UniProt Synonym Protein Names

Semenogelin I

Protein Family

Semenogelin

UniProt Gene Name

SEMG1

UniProt Synonym Gene Names

SEMG; SGI

UniProt Entry Name

SEMG1_HUMAN

NCBI Protein Information

semenogelin-1; SgI-29; cancer/testis antigen 103; semen coagulating protein

NCBI Summary for SEMG1

The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. The antimicrobial peptide SgI-29 is an antimicrobial peptide with antibacterial activity. [provided by RefSeq, Nov 2014]

UniProt Comments for SEMG1

SEMG1: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Belongs to the semenogelin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 20q12-q13.2

Cellular Component: extracellular space; extracellular region; nucleus; secretory granule

Molecular Function: protein binding; structural molecule activity

Biological Process: insemination

Research Articles on SEMG1

1. Data indicate that semenogelin I (Sg I) expression has potential value in predicting renal cell carcinoma (RCC) progression and prognosis, suggesting the use of Sg I as a biomarker for RCC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SEMG1 antibody

Products by Pathway	Pathway Diagram
Amyloids Pathway antibodies	Amyloids Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram

Diseases associated with anti-SEMG1 antibody

Disease Name	Pubmed Publications
Weight Loss Antibodies	>1 publications with SEMG1 and Weight Loss
Breast Neoplasms Antibodies	>1 publications with SEMG1 and Breast Neoplasms
Gastrointestinal Diseases Antibodies	>1 publications with SEMG1 and Gastrointestinal Diseases

Organs/Tissues associated with anti-SEMG1 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>5 publications with SEMG1 and Prostate