Rabbit Anti-SERPINI2 Polyclonal Antibody – Cat# MBS6346389

SERPINI2 Antibody – Rabbit Polyclonal

Name: SERPINI2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6346389
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6346389

The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development,… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SERPINI2, Polyclonal Antibody

Full Product Name

SERPINI2, CT (SERPINI2, MEPI, PI14, Serpin I2, Myoepithelium-derived serine protease inhibitor, Pancpin, Pancreas-specific protein TSA2004, Peptidase inhibitor 14) (MaxLight 490)

Product Gene Name

anti-SERPINI2 antibody

Product Synonym Names

SERPINI2; MEPI; PI14; Serpin I2; Myoepithelium-derived serine protease inhibitor; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

46,145 Da

OMIM

605587

3D Structure

ModBase 3D Structure for O75830

Immunogen

SERPINI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-401 amino acids from the C-terminal region of human SERPINI2.

Conjugate

MaxLight490

Note

Preservative Free

Product Categories/Family for anti-SERPINI2 antibody

Antibodies; Protease Inhibitors

Applications Tested/Suitable for anti-SERPINI2 antibody

Western Blot (WB), FLISA

Application Notes for anti-SERPINI2 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SERPINI2 antibody

Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010). Lim, J., et al. Cell 125(4):801-814(2006). Chang, W.S., et al. Genes Chromosomes Cancer 29(3):240-255(2000). Xiao, G., et al. Proc. Natl. Acad. Sci. U.S.A. 96(7):3700-3705(1999). Ozaki, K., et al. Genes Chromosomes Cancer 22(3):179-185(1998).

Other Notes

Small volumes of anti-SERPINI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINI2 purchase

MBS6346389 is an antibody targeting SERPINI2. Also known as SERPINI2, CT (SERPINI2, MEPI, PI14, Serpin I2, Myoepithelium-derived serine protease inhibitor, Pancpin, Pancreas-specific protein TSA2004, Peptidase inhibitor 14) (MaxLight 490). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINI2. It may not necessarily be applicable to this product.

NCBI GI #

5453886

NCBI GeneID

5276

NCBI Accession #

NP_006208.1

NCBI Related Accession #

NP_001012303.1

UniProt Primary Accession #

O75830

UniProt Related Accession #

O75830

GenBank Nucleotide #

NM_006217.4

NCBI Official Full Name

serpin I2 isoform 2

NCBI Official Synonym Full Names

serpin family I member 2

NCBI Official Symbol

SERPINI2

NCBI Official Synonym Symbols

MEPI; PI14; PANCPIN; TSA2004

UniProt Protein Name

Serpin I2

UniProt Synonym Protein Names

Myoepithelium-derived serine protease inhibitor; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14

Protein Family

Serpin

UniProt Gene Name

SERPINI2

UniProt Synonym Gene Names

MEPI; PI14; PI-14

UniProt Entry Name

SPI2_HUMAN

NCBI Protein Information

serpin I2

NCBI Summary for SERPINI2

The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]

UniProt Comments for SERPINI2

Subcellular location: Secreted

Probable.

Tissue specificity: Expressed in pancreas and adipose tissues. Ref.1

Sequence similarities: Belongs to the serpin family.

Sequence caution: The sequence AAH27859.2 differs from that shown. Reason: Erroneous initiation.

Research Articles on SERPINI2

1. The findings indicate that SERPINI2 is a promising candidate for further investigations of the genetic susceptibility to myopia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SERPINI2 antibody

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>2 publications with SERPINI2 and Lung Neoplasms
Breast Neoplasms Antibodies	>1 publications with SERPINI2 and Breast Neoplasms
Carcinoma Antibodies	>1 publications with SERPINI2 and Carcinoma
Fibrosis Antibodies	>1 publications with SERPINI2 and Fibrosis
Inflammation Antibodies	>1 publications with SERPINI2 and Inflammation
Body Weight Changes Antibodies	>1 publications with SERPINI2 and Body Weight Changes

Organs/Tissues associated with anti-SERPINI2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with SERPINI2 and Brain
Lung Antibodies	>2 publications with SERPINI2 and Lung
Pancreas Antibodies	>2 publications with SERPINI2 and Pancreas
Liver Antibodies	>1 publications with SERPINI2 and Liver