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SIRPB1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6459216

MBS6459216 is an antibody targeting SIRPB1. Also known as SIRPB1 (Signal-Regulatory Protein beta-1 isoform 3, SIRP-beta-1 isoform 3, SIRPB1) (MaxLight 550). Reactive in Human. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SIRPB1, Polyclonal Antibody
Full Product Name
SIRPB1 (Signal-Regulatory Protein beta-1 isoform 3, SIRP-beta-1 isoform 3, SIRPB1) (MaxLight 550)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human SIRPB1. Species Crossreactivity: human
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
43,211 Da
3D Structure
ModBase 3D Structure for Q5TFQ8
Immunogen
KLH conjugated synthetic peptide corresponding to aa17-43 at the N-terminal region of human SIRPB1.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-SIRPB1 antibody

Applications Tested/Suitable for anti-SIRPB1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-SIRPB1 antibody
WB: 1:1000
IHC-P: 1:25
Applications are based on unconjugated antibody.

Product References and Citations for anti-SIRPB1 antibody

Ota T., et al. Nat. Genet. 36:40-45(2004). Bechtel S., et al. BMC Genomics 8:399-399(2007). Deloukas P., et al. Nature 414:865-871(2001). Hatherley D., et al. Mol. Cell 31:266-277(2008).

Other Notes

Small volumes of anti-SIRPB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SIRPB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
signal-regulatory protein beta-1 isoform 3
NCBI Official Synonym Full Names
signal regulatory protein beta 1
NCBI Official Symbol
SIRPB1
NCBI Official Synonym Symbols
CD172b; SIRP-BETA-1
UniProt Protein Name
Signal-regulatory protein beta-1 isoform 3
UniProt Gene Name
SIRPB1
UniProt Synonym Gene Names
SIRP-beta-1 isoform 3
NCBI Protein Information
signal-regulatory protein beta-1

NCBI Summary for SIRPB1

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
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UniProt Comments for SIRPB1

Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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