Rabbit Anti-SIRPB2 Polyclonal Antibody – Cat# MBS6347760

SIRPB2 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SIRPB2 antibody detected the SIRPB2 protein (arrow).

SIRPB2 Antibody – Rabbit Polyclonal

Name: SIRPB2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6347760
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6347760

Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SIRPB2, Polyclonal Antibody

Full Product Name

SIRPB2, CT (SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein) (Biotin)

Product Gene Name

anti-SIRPB2 antibody

Product Synonym Names

SIRPB2; PTPN1L; PTPNS1L3; Signal-regulatory protein beta-2; Protein tyrosine phosphatase non-receptor type substrate 1-like 3; Protein tyrosine phosphatase non-receptor type substrate protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

36,968 Da

3D Structure

ModBase 3D Structure for Q5JXA9

Immunogen

SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the C-terminal region of human SIRPB2.

Conjugate

Biotin

Note

Preservative Free

Product Categories/Family for anti-SIRPB2 antibody

Antibodies; Enzymes; Phosphatase

Applications Tested/Suitable for anti-SIRPB2 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-SIRPB2 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SIRPB2 antibody

Nyati, M.K., et al. Cancer Res. 66(24):11554-11559(2006). van den Berg, T.K., et al. J. Immunol. 175(12):7788-7789(2005). Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99(19):12257-12262(2002).

Other Notes

Small volumes of anti-SIRPB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIRPB2 purchase

MBS6347760 is an antibody targeting SIRPB2. Also known as SIRPB2, CT (SIRPB2, PTPN1L, PTPNS1L3, Signal-regulatory protein beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SIRPB2. It may not necessarily be applicable to this product.

NCBI GI #

171906611

NCBI GeneID

284759

NCBI Accession #

NP_001116434.1

UniProt Primary Accession #

Q5JXA9

UniProt Secondary Accession #

Q6TCH9; B4DLM9; E9PCW6

UniProt Related Accession #

Q5JXA9

GenBank Nucleotide #

NM_001122962.1

NCBI Official Full Name

signal-regulatory protein beta-2 isoform 1

NCBI Official Synonym Full Names

signal-regulatory protein beta 2

NCBI Official Symbol

SIRPB2

NCBI Official Synonym Symbols

PTPN1L; PTPNS1L3; dJ776F14.2

UniProt Protein Name

Signal-regulatory protein beta-2

UniProt Synonym Protein Names

Protein tyrosine phosphatase non-receptor type substrate 1-like 3; Protein tyrosine phosphatase non-receptor type substrate protein

Protein Family

Signal-regulatory protein

UniProt Gene Name

SIRPB2

UniProt Synonym Gene Names

PTPN1L; PTPNS1L3; SIRP-beta-2

UniProt Entry Name

SIRB2_HUMAN

NCBI Protein Information

signal-regulatory protein beta-2; SIRP-beta-2; protein tyrosine phosphatase non-receptor type substrate protein; protein tyrosine phosphatase non-receptor type substrate 1-like 3; protein tyrosine phosphatase, non-receptor type substrate 1-like 3

UniProt Comments for SIRPB2

SIRPB2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: integral to membrane

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SIRPB2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with SIRPB2 and Blood