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SLC25A11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9401953

The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, contains the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SLC25A11, Polyclonal Antibody
Full Product Name
SLC25A11 Antibody
Product Gene Name
anti-SLC25A11 antibody
Product Synonym Names
OGC; SLC20A4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
1.2 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total SLC25A11 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
28,494 Da
OMIM
604165
3D Structure
ModBase 3D Structure for Q02978
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from internal residues of human solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Target Name
SLC25A11

Product Categories/Family for anti-SLC25A11 antibody

Total protein Ab
Applications Tested/Suitable for anti-SLC25A11 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC25A11 antibody
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Testing Data of anti-SLC25A11 antibody

Gel: 12%SDS-PAGE Lysates (from left to right): Human lymphoma tissue Amount of lysate: 40ug per lane Primary antibody: 1/600 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds
Rabbit Anti-SLC25A11 Polyclonal Antibody – Cat# MBS9401953

Immunohistochemistry (IHC) of anti-SLC25A11 antibody

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/30.
Rabbit Anti-SLC25A11 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9401953

Other Notes

Small volumes of anti-SLC25A11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC25A11 purchase

MBS9401953 is an antibody targeting SLC25A11. Also known as SLC25A11 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC25A11. It may not necessarily be applicable to this product.

NCBI GI #
21361114
NCBI GeneID
8402
NCBI Accession #
NP_003553.2
UniProt Primary Accession #
Q02978
UniProt Secondary Accession #
O75537; Q969P7; F5GY65
UniProt Related Accession #
Q02978
GenBank Nucleotide #
NM_003562.4
NCBI Official Full Name
mitochondrial 2-oxoglutarate/malate carrier protein isoform 1
NCBI Official Synonym Full Names
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
NCBI Official Symbol
SLC25A11
NCBI Official Synonym Symbols
OGC; SLC20A4
UniProt Protein Name
Mitochondrial 2-oxoglutarate/malate carrier protein
UniProt Synonym Protein Names
Solute carrier family 25 member 11
Protein Family
Mitochondrial 2-oxoglutarate/malate carrier protein
UniProt Gene Name
SLC25A11
UniProt Synonym Gene Names
SLC20A4; OGCP
UniProt Entry Name
M2OM_HUMAN
NCBI Protein Information
mitochondrial 2-oxoglutarate/malate carrier protein

NCBI Summary for SLC25A11

The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011]

UniProt Comments for SLC25A11

SLC25A11: Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Belongs to the mitochondrial carrier family.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Mitochondrial; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: mitochondrion; integral to plasma membrane; mitochondrial inner membrane; nucleus

Molecular Function: oxoglutarate:malate antiporter activity

Biological Process: transport; alpha-ketoglutarate transport; carbohydrate metabolic process; glucose metabolic process; pathogenesis; gluconeogenesis
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Research Articles on SLC25A11

1. Compares and contrasts all the known human SLC25A* genes and includes functional information.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC25A11 antibody

 Reference Product  PubMed Publications
 MDH2 antibody  >3 publications with SLC25A11 and MDH2
 MDH1 antibody  >1 publications with SLC25A11 and MDH1

Pathways associated with anti-SLC25A11 antibody

 Products by Pathway  Pathway Diagram
 Gluconeogenesis Pathway antibodies  Gluconeogenesis Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-SLC25A11 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >2 publications with SLC25A11 and Liver Diseases
 Liver Cirrhosis Antibodies  >1 publications with SLC25A11 and Liver Cirrhosis
 Heart Diseases Antibodies  >1 publications with SLC25A11 and Heart Diseases
 Liver Neoplasms, Experimental Antibodies  >1 publications with SLC25A11 and Liver Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >1 publications with SLC25A11 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with SLC25A11 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >1 publications with SLC25A11 and Disease Models, Animal
 Liver Neoplasms Antibodies  >1 publications with SLC25A11 and Liver Neoplasms
 Chromosome Aberrations Antibodies  >1 publications with SLC25A11 and Chromosome Aberrations
 Hypertrophy Antibodies  >1 publications with SLC25A11 and Hypertrophy

Organs/Tissues associated with anti-SLC25A11 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with SLC25A11 and Kidney
 Liver Antibodies  >3 publications with SLC25A11 and Liver
 Brain Antibodies  >2 publications with SLC25A11 and Brain
 Heart Antibodies  >1 publications with SLC25A11 and Heart
 Blood Antibodies  >1 publications with SLC25A11 and Blood
 Muscle Antibodies  >1 publications with SLC25A11 and Muscle
 Intestine Antibodies  >1 publications with SLC25A11 and Intestine
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