Rabbit Anti-SLC47A1 Polyclonal Antibody – Cat# MBS9130148

Western blot analysis of extracts of HepG2 cells, using SLC47A1 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

SLC47A1 Antibody – Rabbit Polyclonal

Name: SLC47A1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9130148
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9130148

MBS9130148 is an antibody targeting SLC47A1. Also known as SLC47A1 Polyclonal Antibody. Reactive in Human. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SLC47A1, Polyclonal Antibody

Full Product Name

SLC47A1 Polyclonal Antibody

Product Gene Name

anti-SLC47A1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C. Avoid freeze / thaw cycles.

Molecular Weight

Calculated MW: 62kDa

OMIM

609832

3D Structure

ModBase 3D Structure for Q96FL8

Immunogen

Recombinant protein of human SLC47A1

Product Categories/Family for anti-SLC47A1 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SLC47A1 antibody

Western Blot (WB)

Application Notes for anti-SLC47A1 antibody

WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-SLC47A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC47A1. It may not necessarily be applicable to this product.

NCBI GI #

22907060

NCBI GeneID

55244

NCBI Accession #

NP_060712.2

UniProt Primary Accession #

Q96FL8

UniProt Secondary Accession #

Q53HF5; Q6PD77; Q86VL4; Q9NVA3

UniProt Related Accession #

Q96FL8

GenBank Nucleotide #

NM_018242.2

NCBI Official Full Name

multidrug and toxin extrusion protein 1

NCBI Official Synonym Full Names

solute carrier family 47 member 1

NCBI Official Symbol

SLC47A1

NCBI Official Synonym Symbols

MATE1

UniProt Protein Name

Multidrug and toxin extrusion protein 1

UniProt Synonym Protein Names

Solute carrier family 47 member 1

Protein Family

Multidrug and toxin extrusion protein

UniProt Gene Name

SLC47A1

UniProt Synonym Gene Names

MATE1; MATE-1; hMATE-1

UniProt Entry Name

S47A1_HUMAN

NCBI Protein Information

multidrug and toxin extrusion protein 1

NCBI Summary for SLC47A1

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

UniProt Comments for SLC47A1

SLC47A1: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: drug transporter activity; monovalent cation:proton antiporter activity

Biological Process: multidrug transport; organic cation transport; transmembrane transport

Research Articles on SLC47A1

1. MATE1 sequesters organic cations within an intracellular compartment that has no influence on secretion in renal proximal tubules.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC47A1 antibody

Products by Pathway	Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies	Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-SLC47A1 antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>6 publications with SLC47A1 and Kidney Diseases
Cardiovascular Diseases Antibodies	>3 publications with SLC47A1 and Cardiovascular Diseases
Nervous System Diseases Antibodies	>2 publications with SLC47A1 and Nervous System Diseases
Liver Diseases Antibodies	>2 publications with SLC47A1 and Liver Diseases
Acute Kidney Injury Antibodies	>2 publications with SLC47A1 and Acute Kidney Injury
Cholestasis Antibodies	>1 publications with SLC47A1 and Cholestasis
Hypertension Antibodies	>1 publications with SLC47A1 and Hypertension
Drug-Related Side Effects and Adverse Reactions Antibodies	>1 publications with SLC47A1 and Drug-Related Side Effects and Adverse Reactions
Drug-Induced Liver Injury Antibodies	>1 publications with SLC47A1 and Drug-Induced Liver Injury

Organs/Tissues associated with anti-SLC47A1 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>30 publications with SLC47A1 and Kidney
Liver Antibodies	>15 publications with SLC47A1 and Liver
Brain Antibodies	>4 publications with SLC47A1 and Brain
Ovary Antibodies	>2 publications with SLC47A1 and Ovary
Prostate Antibodies	>1 publications with SLC47A1 and Prostate
Muscle Antibodies	>1 publications with SLC47A1 and Muscle
Eye Antibodies	>1 publications with SLC47A1 and Eye