• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SLCO1C1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9130528
SPECIAL PROMOTION: Get FREE $5 Amazon gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLCO1C1, Polyclonal Antibody
Full Product Name
SLCO1C1 Polyclonal Antibody
Product Gene Name
anti-SLCO1C1 antibody
Product Synonym Names
OATP1; OATPF; OATP-F; OATP14; OATP1C1; OATPRP5; SLC21A14
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
Calculated MW: 79kDa
Molecular Weight: 712
OMIM
613389
3D Structure
ModBase 3D Structure for Q9NYB5
Immunogen
Recombinant protein of human SLCO1C1

Product Categories/Family for anti-SLCO1C1 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SLCO1C1 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-SLCO1C1 antibody
WB: 1:200 - 1:2000, IP: 1:20 - 1:50

Western Blot (WB) of anti-SLCO1C1 antibody

Western blot analysis of extracts of various cell lines, using SLCO1C1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
Rabbit Anti-SLCO1C1 Polyclonal Antibody – Cat# MBS9130528

Other Notes

Small volumes of anti-SLCO1C1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLCO1C1 purchase

MBS9130528 is an antibody targeting SLCO1C1. Also known as SLCO1C1 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLCO1C1. It may not necessarily be applicable to this product.

NCBI GI #
225543114
NCBI GeneID
53919
NCBI Accession #
NP_001139416.1
UniProt Primary Accession #
Q9NYB5
UniProt Secondary Accession #
Q5JPA4; B7Z251; B7Z3Q3; B7Z8P1; F5GZD6
UniProt Related Accession #
Q9NYB5
GenBank Nucleotide #
NM_001145944.1
NCBI Official Full Name
solute carrier organic anion transporter family member 1C1 isoform 4
NCBI Official Synonym Full Names
solute carrier organic anion transporter family member 1C1
NCBI Official Symbol
SLCO1C1
NCBI Official Synonym Symbols
OATP1; OATPF; OATP-F; OATP14; OATP1C1; OATPRP5; SLC21A14
UniProt Protein Name
Solute carrier organic anion transporter family member 1C1
UniProt Synonym Protein Names
Organic anion transporter F; OATP-F; Organic anion transporter polypeptide-related protein 5; OAT-RP-5; OATPRP5; Organic anion-transporting polypeptide 14; OATP-14; Solute carrier family 21 member 14; Thyroxine transporter
Protein Family
Solute carrier organic anion transporter family
UniProt Gene Name
SLCO1C1
UniProt Synonym Gene Names
OATP14; OATP1C1; OATPF; SLC21A14; OATP-F; OAT-RP-5; OATPRP5; OATP-14
UniProt Entry Name
SO1C1_HUMAN
NCBI Protein Information
solute carrier organic anion transporter family member 1C1

UniProt Comments for SLCO1C1

SLCO1C1: Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain. Belongs to the organo anion transporter (TC 2.A.60) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p12.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: bile acid transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; thyroid hormone transmembrane transporter activity

Biological Process: bile acid and bile salt transport; bile acid metabolic process; sodium-independent organic anion transport; transmembrane transport
Show more

Research Articles on SLCO1C1

1. The PDE3A-SLCO1C1 locus rs3794271 SNP showed a highly significant association with anti-TNF treatment response.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLCO1C1 antibody

 Products by Pathway  Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Thyroid Hormone Signaling Pathway antibodies  Thyroid Hormone Signaling Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Organic Anions Pathway antibodies  Transport Of Organic Anions Pathway Diagram
 Transport Of Vitamins, Nucleosides, And Related Molecules Pathway antibodies  Transport Of Vitamins, Nucleosides, And Related Molecules Pathway Diagram

Diseases associated with anti-SLCO1C1 antibody

 Disease Name  Pubmed Publications
 Thyroid Diseases Antibodies  >7 publications with SLCO1C1 and Thyroid Diseases
 Brain Diseases Antibodies  >6 publications with SLCO1C1 and Brain Diseases
 Necrosis Antibodies  >4 publications with SLCO1C1 and Necrosis
 Inflammation Antibodies  >4 publications with SLCO1C1 and Inflammation
 Poisoning Antibodies  >2 publications with SLCO1C1 and Poisoning
 Neurobehavioral Manifestations Antibodies  >2 publications with SLCO1C1 and Neurobehavioral Manifestations
 Drug-Induced Liver Injury Antibodies  >2 publications with SLCO1C1 and Drug-Induced Liver Injury
 Immune System Diseases Antibodies  >2 publications with SLCO1C1 and Immune System Diseases
 Hyperplasia Antibodies  >1 publications with SLCO1C1 and Hyperplasia
 Hypertrophy Antibodies  >1 publications with SLCO1C1 and Hypertrophy

Organs/Tissues associated with anti-SLCO1C1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with SLCO1C1 and Brain
 Thyroid Antibodies  >21 publications with SLCO1C1 and Thyroid
 Kidney Antibodies  >7 publications with SLCO1C1 and Kidney
 Nerve Antibodies  >2 publications with SLCO1C1 and Nerve
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000