Rabbit Anti-SORT1 Polyclonal Antibody – Cat# MBS7106415

SORT1 Antibody – Rabbit Polyclonal

Name: SORT1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS7106415
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7106415

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR).… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SORT1, Polyclonal Antibody

Full Product Name

SORT1 Antibody, FITC conjugated

Product Gene Name

anti-SORT1 antibody

Product Synonym Names

Sortilin; 100 kDa NT receptor; Glycoprotein 95; Gp95; Neurotensin receptor 3; NT3; NTR3; SORT1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

>95%, Protein G purified

Preparation and Storage

Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: SORT1 (MBS7106413)
FITC Conjugated Antibody: SORT1 (MBS7106415)

Molecular Weight

77,375 Da

OMIM

X98248 mRNA

3D Structure

ModBase 3D Structure for Q99523

Immunogen

Recombinant Human Sortilin protein (328-457AA)

Conjugation

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Product Categories/Family for anti-SORT1 antibody

Neuroscience; Cancer; Cardiovascular; Metabolism

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SORT1 antibody

ELISA (EIA)

Other Notes

Small volumes of anti-SORT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SORT1 purchase

MBS7106415 is an antibody targeting SORT1. Also known as SORT1 Antibody, FITC conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SORT1. It may not necessarily be applicable to this product.

NCBI GI #

327315343

NCBI GeneID

6272

NCBI Accession #

NP_001192157.1

UniProt Primary Accession #

Q99523

UniProt Secondary Accession #

Q8IZ49; B4DWI3; C0JYZ0

UniProt Related Accession #

Q99523

GenBank Nucleotide #

NM_001205228.1

NCBI Official Full Name

sortilin isoform 2

NCBI Official Synonym Full Names

sortilin 1

NCBI Official Symbol

SORT1

NCBI Official Synonym Symbols

NT3; Gp95; NTR3; LDLCQ6

UniProt Protein Name

Sortilin

UniProt Synonym Protein Names

100 kDa NT receptor; Glycoprotein 95; Gp95; Neurotensin receptor 3; NT3; NTR3

Protein Family

Sortilin

UniProt Gene Name

SORT1

UniProt Synonym Gene Names

Gp95; NT3; NTR3

NCBI Protein Information

sortilin

NCBI Summary for SORT1

This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Research Articles on SORT1

1. The SNP rs17646665, located in a non-coding region of the SORT1 gene, remained significantly associated with decreased risk of Alzheimer's disease after multiple testing (pc = 0.0061). In addition, other SNPs were found to be nominally associated with risk of Alzheimer's disease, as well as altered cognitive function and the CSF biomarker Abeta42, but these associations did not survive correction for multiple testing.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SORT1 antibody

Reference Product	PubMed Publications
NGFR antibody	>2 publications with SORT1 and NGFR
BDNF antibody	>1 publications with SORT1 and BDNF

Pathways associated with anti-SORT1 antibody

Products by Pathway	Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
Clathrin Derived Vesicle Budding Pathway antibodies	Clathrin Derived Vesicle Budding Pathway Diagram
Golgi Associated Vesicle Biogenesis Pathway antibodies	Golgi Associated Vesicle Biogenesis Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Neurotrophin Signaling Pathway antibodies	Neurotrophin Signaling Pathway Diagram
Neurotrophin Signaling Pathway antibodies	Neurotrophin Signaling Pathway Diagram
P75(NTR)-mediated Signaling Pathway antibodies	P75(NTR)-mediated Signaling Pathway Diagram
Trans-Golgi Network Vesicle Budding Pathway antibodies	Trans-Golgi Network Vesicle Budding Pathway Diagram

Diseases associated with anti-SORT1 antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>33 publications with SORT1 and Cardiovascular Diseases
Heart Diseases Antibodies	>24 publications with SORT1 and Heart Diseases
Coronary Artery Disease Antibodies	>24 publications with SORT1 and Coronary Artery Disease
Atherosclerosis Antibodies	>17 publications with SORT1 and Atherosclerosis
Myocardial Infarction Antibodies	>15 publications with SORT1 and Myocardial Infarction
Nervous System Diseases Antibodies	>11 publications with SORT1 and Nervous System Diseases
Brain Diseases Antibodies	>10 publications with SORT1 and Brain Diseases
Dyslipidemias Antibodies	>8 publications with SORT1 and Dyslipidemias
Liver Diseases Antibodies	>6 publications with SORT1 and Liver Diseases
Carcinoma Antibodies	>5 publications with SORT1 and Carcinoma

Organs/Tissues associated with anti-SORT1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>41 publications with SORT1 and Blood
Heart Antibodies	>24 publications with SORT1 and Heart
Liver Antibodies	>13 publications with SORT1 and Liver
Brain Antibodies	>12 publications with SORT1 and Brain
Nerve Antibodies	>4 publications with SORT1 and Nerve
Lung Antibodies	>4 publications with SORT1 and Lung
Bone Marrow Antibodies	>2 publications with SORT1 and Bone Marrow
Bone Antibodies	>2 publications with SORT1 and Bone
Thyroid Antibodies	>2 publications with SORT1 and Thyroid
Ovary Antibodies	>2 publications with SORT1 and Ovary