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SOX15 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6002007

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SOX15, Polyclonal Antibody
Full Product Name
SOX15, ID (SOX15, SOX12, SOX20, SOX26, SOX27, Protein SOX-15, Protein SOX-12, Protein SOX-20)
Product Gene Name
anti-SOX15 antibody
Product Synonym Names
Anti -SOX15, ID (SOX15, SOX12, SOX20, SOX26, SOX27, Protein SOX-15, Protein SOX-12, Protein SOX-20)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,251 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (7491496..7494037, complement). Location: 17p12.3
OMIM
601297
3D Structure
ModBase 3D Structure for O60248
Immunogen
SOX15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-125 amino acids from the Central region of human SOX15.

Product Categories/Family for anti-SOX15 antibody

Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-SOX15 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SOX15 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-SOX15 antibody

SOX15 Antibody (Center) western blot analysis in human placenta and mouse brain tissue lysates (35ug/lane).This demonstrates the SOX15 antibody detected the SOX15 protein (arrow).
Rabbit Anti-SOX15 Polyclonal Antibody – Cat# MBS6002007

Immunohistochemistry (IHC) of anti-SOX15 antibody

SOX15 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SOX15 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-SOX15 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6002007

Other Notes

Small volumes of anti-SOX15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOX15 purchase

MBS6002007 is an antibody targeting SOX15. Also known as SOX15, ID (SOX15, SOX12, SOX20, SOX26, SOX27, Protein SOX-15, Protein SOX-12, Protein SOX-20). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX15. It may not necessarily be applicable to this product.

NCBI GI #
47938388
NCBI GeneID
6665
NCBI Accession #
AAH72003.1
UniProt Primary Accession #
O60248
UniProt Secondary Accession #
P35717; Q9Y6W7; D3DTQ0
UniProt Related Accession #
O60248
NCBI Official Full Name
SOX15 protein
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 15
NCBI Official Symbol
SOX15
NCBI Official Synonym Symbols
SOX20; SOX26; SOX27
UniProt Protein Name
Protein SOX-15
UniProt Synonym Protein Names
Protein SOX-12; Protein SOX-20
Protein Family
Protein
UniProt Gene Name
SOX15
UniProt Synonym Gene Names
SOX12; SOX20; SOX26; SOX27
UniProt Entry Name
SOX15_HUMAN
NCBI Protein Information
protein SOX-15; SRY (sex determining region Y)-box 20

NCBI Summary for SOX15

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]
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UniProt Comments for SOX15

SOX15: Binds to the 5'-AACAAT-3' sequence.

Protein type: DNA-binding; Transcription factor; Cell development/differentiation

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytoplasm; nucleus

Molecular Function: DNA binding; protein heterodimerization activity; chromatin binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; myoblast development; regulation of transcription, DNA-dependent; male gonad development; skeletal muscle regeneration; positive regulation of satellite cell activation involved in skeletal muscle regeneration; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of striated muscle development; cell differentiation
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Research Articles on SOX15

1. The gain of function studies indicated that sex-determining region Y (SRY)-box 15 (SOX15) activate NR5A1 gene expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SOX15 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with SOX15 and Neoplasms
 Pregnancy Complications Antibodies  >1 publications with SOX15 and Pregnancy Complications
 Necrosis Antibodies  >1 publications with SOX15 and Necrosis

Organs/Tissues associated with anti-SOX15 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >7 publications with SOX15 and Embryonic Tissue
 Testis Antibodies  >6 publications with SOX15 and Testis
 Placenta Antibodies  >3 publications with SOX15 and Placenta
 Pancreas Antibodies  >2 publications with SOX15 and Pancreas
 Ovary Antibodies  >2 publications with SOX15 and Ovary
 Liver Antibodies  >1 publications with SOX15 and Liver
 Lung Antibodies  >1 publications with SOX15 and Lung
 Brain Antibodies  >1 publications with SOX15 and Brain
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