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SRA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3901267

Steroid receptor RNA activator 1 (SRA) was originally identified as a functional non-coding RNA that has been shown to be a coactivator of steroid receptors for androgens (AR), estrogens (ER), glucocorticoids, and progestins (PR). SRA exists in… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SRA, Polyclonal Antibody
Full Product Name
Rabbit anti-SRA Antibody, Affinity Purified
Product Gene Name
Product Synonym Gene Name
SRA1
Product Synonym Names
SRAP; steroid receptor RNA activator 1 (complexes with NCOA1); STRAA1; steroid receptor RNA activator protein; steroid receptor coactivator; pp7684; SRA; steroid receptor RNA activator 1; Steroid receptor RNA activator 1; steroid receptor RNA activator 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
OMIM
603819
3D Structure
ModBase 3D Structure for Q9HD15
Immunogen
Between 174 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-SRA antibody

Applications Tested/Suitable for anti-SRA antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-SRA antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Western Blot (WB) of anti-SRA antibody

Detection of human SRA by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (20 and 4 ug for WB; 1 mg for IP, 20% of IP loaded), MCF-7 (7; 20 ug) and HEK293T (T; 20ug). Antibodies: Affinity purified rabbit anti-SRA antibody MBS3901267 (lot MBS3901267-1) used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate (B). SRA was also immunoprecipitated using rabbit anti-SRA antibody BL2734 at 3 ug/mg lysate. Detection: Chemiluminescence with exposure times of 5 minutes (A) and 10 seconds (B).
Rabbit Anti-SRA Polyclonal Antibody – Cat# MBS3901267

Other Notes

Small volumes of anti-SRA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRA purchase

MBS3901267 is an antibody targeting SRA. Also known as Rabbit anti-SRA Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRA. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Protein Name
Steroid receptor RNA activator 1
UniProt Synonym Protein Names
Steroid receptor RNA activator protein; SRAP
Protein Family
UniProt Gene Name
SRA1
UniProt Synonym Gene Names
SRAP
UniProt Entry Name
SRA1_HUMAN

UniProt Comments for SRA

SRA1: Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. Belongs to the SRA1 family.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 5q31.3

Cellular Component: nucleoplasm; microtubule cytoskeleton; intercellular bridge; cytoplasm; plasma membrane; nucleus; ribonucleoprotein complex

Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription coactivator activity

Biological Process: regulation of apoptosis; cell proliferation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; apoptosis; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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