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SRPRB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9449511

The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane… More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SRPRB, Polyclonal Antibody
Full Product Name
SRPRB Conjugated Antibody
Product Gene Name
anti-SRPRB antibody
Product Synonym Names
APMCF1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Specificity
The antibody detects endogenous levels of total SRPRB protein.
Preparation and Storage
Store at 4 degree C for 6 months.
Molecular Weight
29,702 Da
3D Structure
ModBase 3D Structure for Q9Y5M8
Immunogen
Full length fusion protein
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Applications Tested/Suitable for anti-SRPRB antibody
Most Applications
Application Notes for anti-SRPRB antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-SRPRB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRPRB purchase

MBS9449511 is an antibody targeting SRPRB. Also known as SRPRB Conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRPRB. It may not necessarily be applicable to this product.

NCBI GI #
40850902
NCBI GeneID
58477
NCBI Accession #
BC065299
UniProt Primary Accession #
Q9Y5M8
UniProt Secondary Accession #
Q6P595; Q8N2D8
UniProt Related Accession #
Q9Y5M8
NCBI Official Full Name
Homo sapiens signal recognition particle receptor, B subunit, mRNA
NCBI Official Synonym Full Names
SRP receptor beta subunit
NCBI Official Symbol
SRPRB
NCBI Official Synonym Symbols
APMCF1
UniProt Protein Name
Signal recognition particle receptor subunit beta
UniProt Synonym Protein Names
Protein APMCF1
UniProt Gene Name
SRPRB
UniProt Synonym Gene Names
SR-beta
UniProt Entry Name
SRPRB_HUMAN
NCBI Protein Information
signal recognition particle receptor subunit beta

UniProt Comments for SRPRB

SRPRB: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. Belongs to the SRP receptor beta subunit family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: endoplasmic reticulum membrane; membrane; cytoplasmic microtubule; cytoplasm; integral to membrane

Molecular Function: GTP binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; translation; unfolded protein response; small GTPase mediated signal transduction; gene expression
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Research Articles on SRPRB

1. APMCF1 participates at least partially in cell cycle regulation through regulating genes such as p21 and TIMP3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SRPRB antibody

 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By XBP1(S) Pathway antibodies  Activation Of Chaperone Genes By XBP1(S) Pathway Diagram
 Activation Of Chaperones By IRE1alpha Pathway antibodies  Activation Of Chaperones By IRE1alpha Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Export Pathway antibodies  Protein Export Pathway Diagram
 Protein Export Pathway antibodies  Protein Export Pathway Diagram
 SRP-dependent Cotranslational Protein Targeting To Membrane Pathway antibodies  SRP-dependent Cotranslational Protein Targeting To Membrane Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
 Unfolded Protein Response Pathway antibodies  Unfolded Protein Response Pathway Diagram

Diseases associated with anti-SRPRB antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with SRPRB and Neoplasms
 Liver Neoplasms Antibodies  >2 publications with SRPRB and Liver Neoplasms
 Brain Diseases Antibodies  >1 publications with SRPRB and Brain Diseases
 Liver Diseases Antibodies  >1 publications with SRPRB and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with SRPRB and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-SRPRB antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with SRPRB and Liver
 Brain Antibodies  >2 publications with SRPRB and Brain
 Ovary Antibodies  >1 publications with SRPRB and Ovary
 Lung Antibodies  >1 publications with SRPRB and Lung
 Kidney Antibodies  >1 publications with SRPRB and Kidney
 Amniotic Fluid Antibodies  >1 publications with SRPRB and Amniotic Fluid
 Esophagus Antibodies  >1 publications with SRPRB and Esophagus
 Stomach Antibodies  >1 publications with SRPRB and Stomach
 Testis Antibodies  >1 publications with SRPRB and Testis
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