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SS3R Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9604292

Function: Receptor for somatostatin-14 and-28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.Subunit Structure: Homodimer and heterodimer with SSTR2. Heterodimerization with SSTR2 inactivates SSTR3… More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SS3R, Polyclonal Antibody
Full Product Name
SS3R Antibody
Product Gene Name
Product Synonym Gene Name
SSTR3
Product Synonym Names
OTTHUMP00000028737; Smstr 3; Smstr3; Somatostatin receptor subtype 3; Somatostatin receptor type 3; SS 3R; SS-3-R; SS3-R; SS3R; SSR 28; SSR-28; SSR28; SSR3_HUMAN; Sst 3; Sst3; SSTR 3; SSTR3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Concentration
1mg/ml (lot specific)
Specificity
SS3R antibody detects endogenous levels of total SS3R
Antibody/Peptide Pairs
SS3R peptide (MBS9623009) is used for blocking the activity of SS3R antibody (MBS9604292)
Molecular Weight
Observed: 46 kDa
Predicted: 46 kDa
3D Structure
ModBase 3D Structure for P32745
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide
Subcellular Location
Cell Membrane. Internalized into endoplasmic vesicles upon somatostatin-stimulation.
Tissue Specificity
Brain, pituitary and pancreas.
Predicted Cross Reactivity
Pig, Bovine, Sheep
Similarity
Pig (82%), Bovine (100%), Sheep (100%)
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SS3R antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-SS3R antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-SS3R antibody

Western blot analysis of SS3R expression in Fetal Kidney Lysate, The lane on the left is treated with the antigen-specific peptide.
Rabbit Anti-SS3R Polyclonal Antibody – Cat# MBS9604292

Immunohistochemistry (IHC) of anti-SS3R antibody

MBS9604292 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Rabbit Anti-SS3R Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9604292

Other Notes

Small volumes of anti-SS3R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SS3R purchase

MBS9604292 is an antibody targeting SS3R. Also known as SS3R Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SS3R. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
somatostatin receptor type 3
NCBI Official Synonym Full Names
somatostatin receptor 3
NCBI Official Symbol
SSTR3
NCBI Official Synonym Symbols
SS3R; SS3-R; SS-3-R; SSR-28
UniProt Protein Name
Somatostatin receptor type 3
UniProt Synonym Protein Names
SSR-28
Protein Family
UniProt Gene Name
SSTR3
UniProt Synonym Gene Names
SS-3-R; SS3-R; SS3R
NCBI Protein Information
somatostatin receptor type 3

NCBI Summary for SS3R

This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for SS3R

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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