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SSBP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS820111

MBS820111 is an antibody targeting SSBP1. Reactive in Human. Host: Rabbit. Rabbit polyclonal antibody to SSBP1 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SSBP1, Polyclonal Antibody
Full Product Name
Anti-SSBP1 Antibody
Product Gene Name
anti-SSBP1 antibody
Product Synonym Names
SSBP; Single-stranded DNA-binding protein, mitochondrial; Mt-SSB; MtSSB; PWP1-interacting protein 17
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SSBP1 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
SSBP1 peptide (MBS823948) is used for blocking the activity of SSBP1 antibody (MBS820111)
Molecular Weight
17,260 Da
OMIM
600439
3D Structure
ModBase 3D Structure for Q04837
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SSBP1. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SSBP1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-SSBP1 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/ICC (1/100 - 1/500)

Western Blot (WB) of anti-SSBP1 antibody

Western blot analysis of SSBP1 expression in A375 (A), HeLa (B), MOLT4 (C) whole cell lysates.
Rabbit Anti-SSBP1 Polyclonal Antibody – Cat# MBS820111

Immunohistochemistry (IHC) of anti-SSBP1 antibody

Immunohistochemical analysis of SSBP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-SSBP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS820111

Immunofluorescence (IF) of anti-SSBP1 antibody

Immunofluorescent analysis of SSBP1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Rabbit Anti-SSBP1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS820111

Other Notes

Small volumes of anti-SSBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SSBP1. It may not necessarily be applicable to this product.

NCBI GI #
374671775
NCBI GeneID
6742
NCBI Accession #
NP_001243439.1
UniProt Primary Accession #
Q04837
UniProt Related Accession #
Q04837
GenBank Nucleotide #
NM_001256510.1
NCBI Official Full Name
single-stranded DNA-binding protein, mitochondrial
NCBI Official Synonym Full Names
single-stranded DNA binding protein 1, mitochondrial
NCBI Official Symbol
SSBP1
NCBI Official Synonym Symbols
SSBP; mtSSB; Mt-SSB; SOSS-B1
UniProt Protein Name
Single-stranded DNA-binding protein, mitochondrial
UniProt Synonym Protein Names
PWP1-interacting protein 17
UniProt Gene Name
SSBP1
UniProt Synonym Gene Names
SSBP; Mt-SSB; MtSSB
UniProt Entry Name
SSBP_HUMAN
NCBI Protein Information
single-stranded DNA-binding protein, mitochondrial; PWP1-interacting protein 17

NCBI Summary for SSBP1

SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]

UniProt Comments for SSBP1

SSBP1: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA.

Protein type: RNA-binding; Mitochondrial

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: mitochondrion; mitochondrial matrix; nucleus

Molecular Function: protein binding; chromatin binding; single-stranded DNA binding

Biological Process: positive regulation of helicase activity; mitochondrion organization and biogenesis; organelle organization and biogenesis; DNA replication
Show more

Research Articles on SSBP1

1. In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SSBP1 antibody

 Reference Product  PubMed Publications
 SSBP2 antibody  >6 publications with SSBP1 and SSBP2
 INTS3 antibody  >5 publications with SSBP1 and INTS3
 C9orf80 antibody  >5 publications with SSBP1 and C9orf80
 RBBP8 antibody  >1 publications with SSBP1 and RBBP8

Pathways associated with anti-SSBP1 antibody

 Products by Pathway  Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Mismatch Repair Pathway antibodies  Mismatch Repair Pathway Diagram
 Mismatch Repair Pathway antibodies  Mismatch Repair Pathway Diagram
 Mitochondrial Biogenesis Pathway antibodies  Mitochondrial Biogenesis Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies  Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram

Diseases associated with anti-SSBP1 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >3 publications with SSBP1 and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with SSBP1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with SSBP1 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >2 publications with SSBP1 and Kidney Diseases
 Ovarian Neoplasms Antibodies  >1 publications with SSBP1 and Ovarian Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with SSBP1 and Neoplasm Metastasis
 Skin Diseases Antibodies  >1 publications with SSBP1 and Skin Diseases

Organs/Tissues associated with anti-SSBP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with SSBP1 and Kidney
 Liver Antibodies  >3 publications with SSBP1 and Liver
 Brain Antibodies  >3 publications with SSBP1 and Brain
 Thyroid Antibodies  >2 publications with SSBP1 and Thyroid
 Connective Tissue Antibodies  >1 publications with SSBP1 and Connective Tissue
 Stomach Antibodies  >1 publications with SSBP1 and Stomach
 Blood Antibodies  >1 publications with SSBP1 and Blood
 Embryonic Tissue Antibodies  >1 publications with SSBP1 and Embryonic Tissue
 Placenta Antibodies  >1 publications with SSBP1 and Placenta
 Bone Antibodies  >1 publications with SSBP1 and Bone
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