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STAM2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6351686

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
STAM2, Polyclonal Antibody
Full Product Name
STAM2, ID (STAM2, HBP, Signal transducing adapter molecule 2, Hrs-binding protein) (AP)
Product Gene Name
Product Synonym Names
STAM2; HBP; Signal transducing adapter molecule 2; Hrs-binding protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
58,164 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (152973315..153032506, complement). Location: 2q23.3
OMIM
606244
3D Structure
ModBase 3D Structure for O75886
Immunogen
STAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-172 amino acids from the Central region of human STAM2.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-STAM2 antibody

Applications Tested/Suitable for anti-STAM2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-STAM2 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-STAM2 antibody

STAM2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STAM2 antibody detected the STAM2 protein (arrow).
Rabbit Anti-STAM2 Polyclonal Antibody – Cat# MBS6351686

Product References and Citations for anti-STAM2 antibody

Stuible, M., et al. J. Biol. Chem. 285(31):23899-23907(2010). Rismanchi, N., et al. Traffic 10(2):201-217(2009). Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009). Kong, C., et al. J. Biol. Chem. 282(20):15294-15301(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006).

Other Notes

Small volumes of anti-STAM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAM2 purchase

MBS6351686 is an antibody targeting STAM2. Also known as STAM2, ID (STAM2, HBP, Signal transducing adapter molecule 2, Hrs-binding protein) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STAM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
signal transducing adapter molecule 2
NCBI Official Synonym Full Names
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
NCBI Official Symbol
STAM2
NCBI Official Synonym Symbols
Hbp; STAM2A; STAM2B
UniProt Protein Name
Signal transducing adapter molecule 2
UniProt Synonym Protein Names
Hrs-binding protein
UniProt Gene Name
STAM2
UniProt Synonym Gene Names
HBP; STAM-2
UniProt Entry Name
STAM2_HUMAN
NCBI Protein Information
signal transducing adapter molecule 2; STAM-2; HSE1 homolog; Hrs-binding protein; STAM-like protein containing SH3 and ITAM domains 2

UniProt Comments for STAM2

STAM2: an adaptor protein involved in the downstream signaling of cytokine receptors. Contain a SH3 domain and immunoreceptor tyrosine-based activation motif (ITAM). Acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. May modulate the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q23.3

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; early endosome membrane; cytoplasm; cytosol

Molecular Function: protein binding

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; intracellular protein transport; endosome transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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