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STMN3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6352142

The protein encoded by this gene belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
STMN3, Polyclonal Antibody
Full Product Name
STMN3, CT (STMN3, SCLIP, Stathmin-3, SCG10-like protein) (MaxLight 405)
Product Gene Name
Product Synonym Names
STMN3; SCLIP; Stathmin-3; SCG10-like protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
21,017 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (62271061..62284780, complement). Location: 20q13.3
OMIM
608362
3D Structure
ModBase 3D Structure for Q9NZ72
Immunogen
STMN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-177 amino acids from the C-terminal region of human STMN3.
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-STMN3 antibody

Applications Tested/Suitable for anti-STMN3 antibody
Western Blot (WB), FLISA
Application Notes for anti-STMN3 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-STMN3 antibody

Ng, D.C., et al. Biochem. J. 425(1):95-105(2010). Mahapatra, N.R., et al. Biochemistry 47(27):7167-7178(2008). Bieche, I., et al. Genomics 81(4):400-410(2003). Deloukas, P., et al. Nature 414(6866):865-871(2001). Charbaut, E., et al. J. Biol. Chem. 276(19):16146-16154(2001).

Other Notes

Small volumes of anti-STMN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STMN3 purchase

MBS6352142 is an antibody targeting STMN3. Also known as STMN3, CT (STMN3, SCLIP, Stathmin-3, SCG10-like protein) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STMN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
stathmin-3 isoform 1
NCBI Official Synonym Full Names
stathmin-like 3
NCBI Official Symbol
STMN3
NCBI Official Synonym Symbols
SCLIP
UniProt Protein Name
Stathmin-3
UniProt Synonym Protein Names
SCG10-like protein
Protein Family
UniProt Gene Name
STMN3
UniProt Synonym Gene Names
SCLIP
UniProt Entry Name
STMN3_HUMAN
NCBI Protein Information
stathmin-3; SCG10-like protein; SCG10-like-protein

NCBI Summary for STMN3

This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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UniProt Comments for STMN3

STMN3: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. Belongs to the stathmin family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 20q13.3

Cellular Component: Golgi apparatus; neuron projection; growth cone; axon; cytoplasm

Molecular Function: tubulin binding; protein domain specific binding

Biological Process: negative regulation of Rac protein signal transduction; nervous system development; microtubule depolymerization; regulation of microtubule polymerization or depolymerization; cytoplasmic microtubule organization and biogenesis; neurite development; regulation of cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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