Rabbit Anti-STRA13 Polyclonal Antibody – Cat# MBS7002536

Immunohistochemistry of paraffin-embedded human thymus tissue using MBS7002536 at dilution of 1:100

STRA13 Antibody – Rabbit Polyclonal

Name: STRA13 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS7002536
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7002536

DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

STRA13, Polyclonal Antibody

Full Product Name

STRA13 Antibody

Product Gene Name

anti-STRA13 antibody

Product Synonym Names

Centromere protein X; CENP-X; FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; Retinoic acid-inducible gene D9 protein homolog; Stimulated by retinoic acid gene 13 protein homolog; STRA13; CENPX; FAAP10; MHF2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

>95%,Protein G purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Matching Pairs

Unconjugated Antibody: STRA13 (MBS7002536)
Biotin Conjugated Antibody: STRA13 (MBS7003913)

Matching Pairs

Unconjugated Antibody: STRA13 (MBS7002536)
HRP Conjugated Antibody: STRA13 (MBS7005345)

Molecular Weight

6,466 Da

OMIM

615128

3D Structure

ModBase 3D Structure for A8MT69

Immunogen

Recombinant human Centromere protein X protein

Conjugation

Non-conjugated

Storage Buffer

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-169459

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-STRA13 antibody

ELISA (EIA), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-STRA13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STRA13 purchase

MBS7002536 is an antibody targeting STRA13. Also known as STRA13 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STRA13. It may not necessarily be applicable to this product.

NCBI GI #

401871066

NCBI GeneID

201254

NCBI Accession #

NP_001257935.1

UniProt Primary Accession #

A8MT69

UniProt Secondary Accession #

O00281; O00282; Q96DD4; Q96F51

UniProt Related Accession #

A8MT69

GenBank Nucleotide #

NM_001271006.1

NCBI Official Full Name

centromere protein X isoform 1

NCBI Official Synonym Full Names

stimulated by retinoic acid 13

NCBI Official Symbol

STRA13

NCBI Official Synonym Symbols

D9; MHF2; CENPX; CENP-X; FAAP10

UniProt Protein Name

Centromere protein X

UniProt Synonym Protein Names

FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; Retinoic acid-inducible gene D9 protein homolog; Stimulated by retinoic acid gene 13 protein homolog

Protein Family

Centromere protein

UniProt Gene Name

STRA13

UniProt Synonym Gene Names

CENPX; FAAP10; MHF2; CENP-X

UniProt Entry Name

CENPX_HUMAN

NCBI Protein Information

centromere protein X

UniProt Comments for STRA13

STRA13: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation. Belongs to the CENPX family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Cell cycle regulation

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: nucleoplasm

Molecular Function: DNA binding; double-stranded DNA binding; protein binding

Biological Process: cell division; DNA repair; DNA replication-independent nucleosome assembly at centromere; kinetochore assembly; mitosis; nucleosome assembly; positive regulation of protein ubiquitination; replication fork processing; resolution of meiotic joint molecules as recombinants

Research Articles on STRA13

1. MHF prefers branched DNA over dsDNA because it engages two duplex arms. MHF engages DNA forks or various four-way junctions independent of the junction-site structure. The DNA-binding interface of MHF is important for cellular resistance to DNA damage.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STRA13 antibody

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Chromosome Maintenance Pathway antibodies	Chromosome Maintenance Pathway Diagram
DNA Repair Pathway antibodies	DNA Repair Pathway Diagram
Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway antibodies	Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Nucleosome Assembly Pathway antibodies	Nucleosome Assembly Pathway Diagram

Diseases associated with anti-STRA13 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>6 publications with STRA13 and Breast Neoplasms
Kidney Diseases Antibodies	>5 publications with STRA13 and Kidney Diseases
Liver Diseases Antibodies	>4 publications with STRA13 and Liver Diseases
Necrosis Antibodies	>4 publications with STRA13 and Necrosis
Adenocarcinoma Antibodies	>3 publications with STRA13 and Adenocarcinoma
Lung Neoplasms Antibodies	>3 publications with STRA13 and Lung Neoplasms
Cardiovascular Diseases Antibodies	>3 publications with STRA13 and Cardiovascular Diseases
Neoplasms, Experimental Antibodies	>2 publications with STRA13 and Neoplasms, Experimental
Carcinoma, Hepatocellular Antibodies	>1 publications with STRA13 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with STRA13 and Liver Neoplasms

Organs/Tissues associated with anti-STRA13 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>12 publications with STRA13 and Blood
Embryonic Tissue Antibodies	>11 publications with STRA13 and Embryonic Tissue
Liver Antibodies	>10 publications with STRA13 and Liver
Kidney Antibodies	>7 publications with STRA13 and Kidney
Lung Antibodies	>6 publications with STRA13 and Lung
Placenta Antibodies	>5 publications with STRA13 and Placenta
Bone Antibodies	>5 publications with STRA13 and Bone
Connective Tissue Antibodies	>4 publications with STRA13 and Connective Tissue
Heart Antibodies	>4 publications with STRA13 and Heart
Vascular Antibodies	>4 publications with STRA13 and Vascular