Rabbit Anti-SUGT1 Polyclonal Antibody – Cat# MBS6352456

SUGT1 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the SUGT1 antibody detected the SUGT1 protein (arrow).

SUGT1 Antibody – Rabbit Polyclonal

Name: SUGT1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6352456
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6352456

This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SUGT1, Polyclonal Antibody

Full Product Name

SUGT1, CT (SUGT1, Suppressor of G2 allele of SKP1 homolog, Protein 40-6-3, Sgt1) (AP)

Product Gene Name

anti-SUGT1 antibody

Product Synonym Names

SUGT1; Suppressor of G2 allele of SKP1 homolog; Protein 40-6-3; Sgt1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

37,805 Da

OMIM

604098

3D Structure

ModBase 3D Structure for Q9Y2Z0

Immunogen

SUGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 329-356 amino acids selected from the C-terminal region of human SUGT1.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-SUGT1 antibody

Antibodies; Proteins

Applications Tested/Suitable for anti-SUGT1 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-SUGT1 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SUGT1 antibody

Davies, A.E., et al. J. Cell Biol. 189(2):261-274(2010). Iwatsuki, M., et al. Int. J. Oncol. 36(3):569-575(2010). Bansal, P.K., et al. J. Biol. Chem. 284(28):18692-18698(2009). Zabka, M., et al. Biochem. Biophys. Res. Commun. 370(1):179-183(2008). Spiechowicz, M., et al. Biochem. Biophys. Res. Commun. 357(4):1148-1153(2007).

Other Notes

Small volumes of anti-SUGT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SUGT1 purchase

MBS6352456 is an antibody targeting SUGT1. Also known as SUGT1, CT (SUGT1, Suppressor of G2 allele of SKP1 homolog, Protein 40-6-3, Sgt1) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SUGT1. It may not necessarily be applicable to this product.

NCBI GI #

195963398

NCBI GeneID

10910

NCBI Accession #

NP_001124384.1

UniProt Primary Accession #

Q9Y2Z0

UniProt Secondary Accession #

Q5JAK5; Q5TAM6; Q6VXY6; A2A303

UniProt Related Accession #

Q9Y2Z0

GenBank Nucleotide #

NM_001130912.1

NCBI Official Full Name

suppressor of G2 allele of SKP1 homolog isoform SGT1B

NCBI Official Synonym Full Names

SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)

NCBI Official Symbol

SUGT1

NCBI Official Synonym Symbols

SGT1

UniProt Protein Name

Suppressor of G2 allele of SKP1 homolog

UniProt Synonym Protein Names

Protein 40-6-3; Sgt1

UniProt Gene Name

SUGT1

UniProt Entry Name

SUGT1_HUMAN

NCBI Protein Information

suppressor of G2 allele of SKP1 homolog; SGT1B protein; putative 40-6-3 protein; suppressor of G2 allele of SKP1, S. cerevisiae, homolog of

UniProt Comments for SUGT1

SUGT1: a protein involved in kinetochore function and required for the G1/S and G2/M transitions. A subunit of both core kinetochore and SCF (Skp1-Cul1-F-box) ubiquitin ligase complexes. Two alternatively spliced isoforms have been reported.

Protein type: Ubiquitin conjugating system; Cell cycle regulation

Chromosomal Location of Human Ortholog: 13q14.3

Cellular Component: kinetochore; cytoplasm; cytosol; nucleus; ubiquitin ligase complex

Molecular Function: protein binding

Biological Process: mitosis; innate immune response

Research Articles on SUGT1

1. Data suggest that SspH2 (ubiquitin ligase effector from Salmonella typhimurium) ubiquitination activity and protein stability is enhanced by SGT1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SUGT1 antibody

Reference Product	PubMed Publications
SKP1 antibody	>8 publications with SUGT1 and SKP1
NOD1 antibody	>3 publications with SUGT1 and NOD1
PHLPP1 antibody	>1 publications with SUGT1 and PHLPP1

Pathways associated with anti-SUGT1 antibody

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Inflammasomes Pathway antibodies	Inflammasomes Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
NOD Pathway antibodies	NOD Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways antibodies	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways Diagram
The NLRP3 Inflammasome Pathway antibodies	The NLRP3 Inflammasome Pathway Diagram

Diseases associated with anti-SUGT1 antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>2 publications with SUGT1 and Cardiovascular Diseases
Heart Failure Antibodies	>2 publications with SUGT1 and Heart Failure
Heart Diseases Antibodies	>2 publications with SUGT1 and Heart Diseases
Neoplasms, Experimental Antibodies	>1 publications with SUGT1 and Neoplasms, Experimental
Fibrosis Antibodies	>1 publications with SUGT1 and Fibrosis
Inflammation Antibodies	>1 publications with SUGT1 and Inflammation
Cardiomyopathies Antibodies	>1 publications with SUGT1 and Cardiomyopathies

Organs/Tissues associated with anti-SUGT1 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>5 publications with SUGT1 and Muscle
Brain Antibodies	>4 publications with SUGT1 and Brain
Heart Antibodies	>2 publications with SUGT1 and Heart
Blood Antibodies	>2 publications with SUGT1 and Blood
Lung Antibodies	>2 publications with SUGT1 and Lung
Bone Antibodies	>1 publications with SUGT1 and Bone
Liver Antibodies	>1 publications with SUGT1 and Liver
Stomach Antibodies	>1 publications with SUGT1 and Stomach
Testis Antibodies	>1 publications with SUGT1 and Testis