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SULT1B1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6352521

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and… More details

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Product Overview

Online Datasheet in PDF
Product Name
SULT1B1, Polyclonal Antibody
Full Product Name
SULT1B1, CT (SULT1B1, ST1B2, SULT1B2, Sulfotransferase family cytosolic 1B member 1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase) (PE)
Product Gene Name
anti-SULT1B1 antibody
Product Synonym Names
SULT1B1; ST1B2; SULT1B2; Sulfotransferase family cytosolic 1B member 1; Sulfotransferase 1B2; Thyroid hormone sulfotransferase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
34,899 Da
OMIM
608436
3D Structure
ModBase 3D Structure for O43704
Immunogen
SULT1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the C-terminal region of human SULT1B1.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-SULT1B1 antibody

Antibodies; Enzymes; Sulfotransferase
Applications Tested/Suitable for anti-SULT1B1 antibody
Western Blot (WB), FLISA
Application Notes for anti-SULT1B1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SULT1B1 antibody

SULT1B1 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SULT1B1 antibody detected the SULT1B1 protein (arrow).
Rabbit Anti-SULT1B1 Polyclonal Antibody – Cat# MBS6352521

Western Blot (WB) of anti-SULT1B1 antibody

Western blot analysis of SULT1B1 (arrow) using rabbit polyclonal SULT1B1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SULT1B1 gene.
Rabbit Anti-SULT1B1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6352521

Product References and Citations for anti-SULT1B1 antibody

Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009). Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009). Allali-Hassani, A., et al. PLoS Biol. 5 (5), E97 (2007): Dombrovski, L., et al. Proteins 64(4):1091-1094(2006). Meinl, W., et al. Biochem. Biophys. Res. Commun. 288(4):855-862(2001).

Other Notes

Small volumes of anti-SULT1B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SULT1B1 purchase

MBS6352521 is an antibody targeting SULT1B1. Also known as SULT1B1, CT (SULT1B1, ST1B2, SULT1B2, Sulfotransferase family cytosolic 1B member 1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SULT1B1. It may not necessarily be applicable to this product.

NCBI GI #
29550928
NCBI GeneID
27284
NCBI Accession #
NP_055280.2
UniProt Primary Accession #
O43704
UniProt Secondary Accession #
O15497; Q96FI1; Q9UK34
UniProt Related Accession #
O43704
GenBank Nucleotide #
NM_014465.3
NCBI Official Full Name
sulfotransferase family cytosolic 1B member 1
NCBI Official Synonym Full Names
sulfotransferase family, cytosolic, 1B, member 1
NCBI Official Symbol
SULT1B1
NCBI Official Synonym Symbols
ST1B1; ST1B2; SULT1B2
UniProt Protein Name
Sulfotransferase family cytosolic 1B member 1
UniProt Synonym Protein Names
Sulfotransferase 1B2; ST1B2; Thyroid hormone sulfotransferase
Protein Family
Sulfotransferase family cytosolic
UniProt Gene Name
SULT1B1
UniProt Synonym Gene Names
ST1B2; SULT1B2; ST1B1; Sulfotransferase 1B1; ST1B2
UniProt Entry Name
ST1B1_HUMAN
NCBI Protein Information
sulfotransferase family cytosolic 1B member 1; sulfotransferase 1B1; sulfotransferase 1B2; thyroid hormone sulfotransferase

UniProt Comments for SULT1B1

SULT1B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. Belongs to the sulfotransferase 1 family.

Protein type: Transferase; EC 2.8.2.-

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: cytosol

Molecular Function: sulfotransferase activity; aryl sulfotransferase activity

Biological Process: steroid metabolic process; biogenic amine metabolic process; flavonoid metabolic process; epithelial cell differentiation; xenobiotic metabolic process; sulfation; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; thyroid hormone metabolic process; phenol metabolic process
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Research Articles on SULT1B1

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SULT1B1 antibody

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cytosolic Sulfonation Of Small Molecules Pathway antibodies  Cytosolic Sulfonation Of Small Molecules Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway antibodies  Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway Diagram
 Defective GGT1 Causes Glutathionuria (GLUTH) Pathway antibodies  Defective GGT1 Causes Glutathionuria (GLUTH) Pathway Diagram
 Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway antibodies  Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway Diagram
 Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway antibodies  Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway Diagram
 Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway antibodies  Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway Diagram
 Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway antibodies  Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway Diagram
 Defective TPMT Causes Thiopurine S-methyltransferase Deficiency (TPMT Deficiency) Pathway antibodies  Defective TPMT Causes Thiopurine S-methyltransferase Deficiency (TPMT Deficiency) Pathway Diagram

Diseases associated with anti-SULT1B1 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >3 publications with SULT1B1 and Liver Diseases
 Inflammation Antibodies  >2 publications with SULT1B1 and Inflammation
 Brain Diseases Antibodies  >1 publications with SULT1B1 and Brain Diseases
 Hyperglycemia Antibodies  >1 publications with SULT1B1 and Hyperglycemia
 Neoplasms, Experimental Antibodies  >1 publications with SULT1B1 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >1 publications with SULT1B1 and Kidney Diseases
 Fatty Liver Antibodies  >1 publications with SULT1B1 and Fatty Liver

Organs/Tissues associated with anti-SULT1B1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >10 publications with SULT1B1 and Kidney
 Connective Tissue Antibodies  >1 publications with SULT1B1 and Connective Tissue
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