Rabbit Anti-SULT1C2 Polyclonal Antibody – Cat# MBS6501490

Western blot analysis of anti-SULT1C2 Pab in mouse liver tissue lysate (35ug/lane). SULT1C2(arrow) was detected using the purified Pab.

SULT1C2 Antibody – Rabbit Polyclonal

Name: SULT1C2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6501490
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6501490

MBS6501490 is an antibody targeting SULT1C2. Also known as SULT1C2, NT (Sulfotransferase 1C4, ST1C4, Sulfotransferase 1C2, SULT1C#2, SULT1C4) (FITC). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SULT1C2, Polyclonal Antibody

Full Product Name

SULT1C2, NT (Sulfotransferase 1C4, ST1C4, Sulfotransferase 1C2, SULT1C#2, SULT1C4) (FITC)

Product Gene Name

anti-SULT1C2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein G Affinity Chromatography.

Specificity

Recognizes human SULT1C2.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

37.6kDa (322aa), confirmed by MALDI-TOF

OMIM

608357

3D Structure

ModBase 3D Structure for O75897

Immunogen

Synthetic peptide selected from the N-terminal region of human SULT1C2 (KLH).

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-SULT1C2 antibody

Antibodies; Enzymes; Sulfotransferase

Applications Tested/Suitable for anti-SULT1C2 antibody

Western Blot (WB), FLISA

Application Notes for anti-SULT1C2 antibody

WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SULT1C2 antibody

1. Mutat. Res. 482(1-2), 27-40 (2001). 2. Chem. Biol. Interact. 129(1-2), 141-170 (2000). 3. Genomics 65(2), 157-165 (2000). 4. J. Biol. Chem. 273(51), 33929-33935 (1998). 5. FASEB J. 11(1), 3-14 (1997).

Other Notes

Small volumes of anti-SULT1C2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SULT1C2. It may not necessarily be applicable to this product.

NCBI GI #

28830308

NCBI GeneID

27233

NCBI Accession #

NP_006579

UniProt Primary Accession #

O75897

UniProt Secondary Accession #

Q069I8; Q08AS5; Q53S63

UniProt Related Accession #

O75897

GenBank Nucleotide #

NM_006588.3

NCBI Official Full Name

sulfotransferase 1C4 isoform 1

NCBI Official Synonym Full Names

sulfotransferase family 1C member 4

NCBI Official Symbol

SULT1C4

NCBI Official Synonym Symbols

SULT1C; SULT1C2

UniProt Protein Name

Sulfotransferase 1C4

UniProt Synonym Protein Names

Sulfotransferase 1C2; SULT1C#2

Protein Family

Sulfotransferase

UniProt Gene Name

SULT1C4

UniProt Synonym Gene Names

SULT1C2; ST1C4; SULT1C#2

UniProt Entry Name

ST1C4_HUMAN

NCBI Protein Information

sulfotransferase 1C4

NCBI Summary for SULT1C2

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. [provided by RefSeq, Jul 2008]

UniProt Comments for SULT1C2

SULT1C4: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Belongs to the sulfotransferase 1 family.

Protein type: EC 2.8.2.-; Transferase

Chromosomal Location of Human Ortholog: 2q12.3

Cellular Component: cytosol

Molecular Function: sulfotransferase activity

Biological Process: xenobiotic metabolic process; sulfation; 3'-phosphoadenosine 5'-phosphosulfate metabolic process

Research Articles on SULT1C2

1. The current study aimed to identify the human cytosolic sulfotransferase(s) that is(are) capable of sulfating doxorubicin and its analog epirubicin, and to verify whether sulfation of doxorubicin and epirubicin may occur under metabolic conditions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SULT1C2 antibody

Products by Pathway	Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Cytosolic Sulfonation Of Small Molecules Pathway antibodies	Cytosolic Sulfonation Of Small Molecules Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metapathway Biotransformation antibodies	Metapathway Biotransformation Diagram
Phase II Conjugation Pathway antibodies	Phase II Conjugation Pathway Diagram
Sulfation Biotransformation Reaction Pathway antibodies	Sulfation Biotransformation Reaction Pathway Diagram

Diseases associated with anti-SULT1C2 antibody

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>2 publications with SULT1C2 and Liver Diseases
Kidney Neoplasms Antibodies	>1 publications with SULT1C2 and Kidney Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with SULT1C2 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with SULT1C2 and Liver Neoplasms
Fatty Liver Antibodies	>1 publications with SULT1C2 and Fatty Liver

Organs/Tissues associated with anti-SULT1C2 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2 publications with SULT1C2 and Lung
Kidney Antibodies	>1 publications with SULT1C2 and Kidney