Rabbit Anti-TCEB3 Polyclonal Antibody – Cat# MBS6354425

TCEB3 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TCEB3 antibody detected the TCEB3 protein (arrow).

TCEB3 Antibody – Rabbit Polyclonal

Name: TCEB3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6354425
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6354425

This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TCEB3, Polyclonal Antibody

Full Product Name

TCEB3, ID (TCEB3, Transcription elongation factor B polypeptide 3, Elongin 110kD subunit, Elongin-A, RNA polymerase II transcription factor SIII subunit A1, SIII p110) (AP)

Product Gene Name

anti-TCEB3 antibody

Product Synonym Names

TCEB3; Transcription elongation factor B polypeptide 3; Elongin 110kD subunit; Elongin-A; RNA polymerase II transcription factor SIII subunit A1; SIII p110

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

89,909 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (24069856..24088549). Location: 1p36.1

OMIM

600786

3D Structure

ModBase 3D Structure for Q14241

Immunogen

TCEB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-282 amino acids from the Central region of human TCEB3.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-TCEB3 antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-TCEB3 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-TCEB3 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-TCEB3 antibody

Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009): Olsen, J.V., et al. Cell 127(3):635-648(2006). Woo, J.S., et al. EMBO J. 25(6):1353-1363(2006). Andersen, J.S., et al. Nature 433(7021):77-83(2005). Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004).

Other Notes

Small volumes of anti-TCEB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TCEB3 purchase

MBS6354425 is an antibody targeting TCEB3. Also known as TCEB3, ID (TCEB3, Transcription elongation factor B polypeptide 3, Elongin 110kD subunit, Elongin-A, RNA polymerase II transcription factor SIII subunit A1, SIII p110) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TCEB3. It may not necessarily be applicable to this product.

NCBI GI #

208022641

NCBI GeneID

6924

NCBI Accession #

NP_003189.2

UniProt Primary Accession #

Q14241

UniProt Secondary Accession #

Q8IXH1; B2R7Q8

UniProt Related Accession #

Q14241

GenBank Nucleotide #

NM_003198.2

NCBI Official Full Name

transcription elongation factor B polypeptide 3

NCBI Official Synonym Full Names

transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)

NCBI Official Symbol

TCEB3

NCBI Official Synonym Symbols

EloA; SIII; TCEB3A; SIII p110

UniProt Protein Name

Transcription elongation factor B polypeptide 3

UniProt Synonym Protein Names

Elongin 110 kDa subunit; Elongin-A; EloA; RNA polymerase II transcription factor SIII subunit A1; SIII p110

Protein Family

Transcription elongation factor B polypeptide

UniProt Gene Name

TCEB3

UniProt Synonym Gene Names

EloA

UniProt Entry Name

ELOA1_HUMAN

NCBI Protein Information

transcription elongation factor B polypeptide 3; elongin-A; elongin 110 kDa subunit; transcription elongation factor B alpha subunit; RNA polymerase II transcription factor SIII subunit A1

UniProt Comments for TCEB3

TCEB3: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Heterotrimer of an A (A1, A2 or A3), B and C subunit. The C subunit mediates the binding of the elongin BC complex to subunit A.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 1p36.1

Cellular Component: nucleoplasm; extracellular space; cytoplasm; integral to membrane; nucleus

Molecular Function: DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TCEB3 antibody

Products by Pathway	Pathway Diagram
Formation And Maturation Of MRNA Transcript Pathway antibodies	Formation And Maturation Of MRNA Transcript Pathway Diagram
Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
Formation Of HIV-1 Elongation Complex In The Absence Of HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex In The Absence Of HIV-1 Tat Pathway Diagram
Formation Of RNA Pol II Elongation Complex Pathway antibodies	Formation Of RNA Pol II Elongation Complex Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram
HIV-1 Transcription Elongation Pathway antibodies	HIV-1 Transcription Elongation Pathway Diagram
HIV-1 Elongation Arrest And Recovery Pathway antibodies	HIV-1 Elongation Arrest And Recovery Pathway Diagram
Late Phase Of HIV Life Cycle Pathway antibodies	Late Phase Of HIV Life Cycle Pathway Diagram

Diseases associated with anti-TCEB3 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with TCEB3 and Neoplasms
Neuroblastoma Antibodies	>1 publications with TCEB3 and Neuroblastoma

Organs/Tissues associated with anti-TCEB3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with TCEB3 and Blood