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TDRD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7045220

Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of… More details

$230 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TDRD1, Polyclonal Antibody
Full Product Name
TDRD1 Antibody
Product Gene Name
anti-TDRD1 antibody
Product Synonym Names
Tudor domain-containing protein 1; Cancer/testis antigen 41.1; CT41.1; TDRD1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: TDRD1 (MBS7045220)
FITC Conjugated Antibody: TDRD1 (MBS7043748)
Matching Pairs
Unconjugated Antibody: TDRD1 (MBS7045220)
Biotin Conjugated Antibody: TDRD1 (MBS7045580)
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Molecular Weight
79,170 Da
OMIM
605796
3D Structure
ModBase 3D Structure for Q9BXT4
Species
Human
Immunogen
Recombinant human Tudor domain-containing protein 1 protein
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165663
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TDRD1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-TDRD1 antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7045220 at dilution of 1:100
Rabbit Anti-TDRD1 Polyclonal Antibody – Cat# MBS7045220

Immunofluorescence (IF) of anti-TDRD1 antibody

Immunofluorescent analysis of Hela cells using MBS7045220 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-TDRD1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS7045220

Other Notes

Small volumes of anti-TDRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TDRD1 purchase

MBS7045220 is an antibody targeting TDRD1. Also known as TDRD1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TDRD1. It may not necessarily be applicable to this product.

NCBI GI #
38505161
NCBI GeneID
56165
NCBI Accession #
NP_942090.1
UniProt Primary Accession #
Q9BXT4
UniProt Secondary Accession #
Q4G0Y8; Q6P518; Q9H7B3; A6NEN3; A6NMN2; B3KVI4; B4E2L5; D3DRC2
UniProt Related Accession #
Q9BXT4
GenBank Nucleotide #
NM_198795.1
NCBI Official Full Name
tudor domain-containing protein 1
NCBI Official Synonym Full Names
tudor domain containing 1
NCBI Official Symbol
TDRD1
NCBI Official Synonym Symbols
CT41.1
UniProt Protein Name
Tudor domain-containing protein 1
UniProt Synonym Protein Names
Cancer/testis antigen 41.1; CT41.1
Protein Family
Tudor domain-containing protein
UniProt Gene Name
TDRD1
UniProt Synonym Gene Names
CT41.1
UniProt Entry Name
TDRD1_HUMAN
NCBI Protein Information
tudor domain-containing protein 1

NCBI Summary for TDRD1

This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for TDRD1

TDRD1: Plays a central role during spermatogenesis by participating in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins. Belongs to the TDRD1 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 10q25.3

Cellular Component: cytoplasm

Biological Process: DNA methylation during gametogenesis; germ cell development; RNA-mediated gene silencing; spermatogenesis
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Research Articles on TDRD1

1. ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TDRD1 antibody

 Reference Product  PubMed Publications
 PIWIL2 antibody  >13 publications with TDRD1 and PIWIL2
 PIWIL1 antibody  >11 publications with TDRD1 and PIWIL1
 PIWIL4 antibody  >6 publications with TDRD1 and PIWIL4
 DDX4 antibody  >5 publications with TDRD1 and DDX4
 NANOS2 antibody  >1 publications with TDRD1 and NANOS2
 ASZ1 antibody  >1 publications with TDRD1 and ASZ1
 MOV10L1 antibody  >1 publications with TDRD1 and MOV10L1

Pathways associated with anti-TDRD1 antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Gene Silencing By RNA Pathway antibodies  Gene Silencing By RNA Pathway Diagram
 PIWI-interacting RNA (piRNA) Biogenesis Pathway antibodies  PIWI-interacting RNA (piRNA) Biogenesis Pathway Diagram

Diseases associated with anti-TDRD1 antibody

 Disease Name  Pubmed Publications
 Infertility, Female Antibodies  >2 publications with TDRD1 and Infertility, Female
 Testicular Diseases Antibodies  >1 publications with TDRD1 and Testicular Diseases
 Adenocarcinoma Antibodies  >1 publications with TDRD1 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >1 publications with TDRD1 and Cell Transformation, Neoplastic
 Hyperplasia Antibodies  >1 publications with TDRD1 and Hyperplasia
 Neoplasm Metastasis Antibodies  >1 publications with TDRD1 and Neoplasm Metastasis

Organs/Tissues associated with anti-TDRD1 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >17 publications with TDRD1 and Testis
 Prostate Antibodies  >8 publications with TDRD1 and Prostate
 Liver Antibodies  >2 publications with TDRD1 and Liver
 Brain Antibodies  >2 publications with TDRD1 and Brain
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