TK1 Antibody – Rabbit Polyclonal

TK: cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.

Protein type: EC 2.7.1.21; Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes; Kinase, other

Chromosomal Location of Human Ortholog: 17q23.2-q25.3

Cellular Component: cytosol

Molecular Function: ATP binding; identical protein binding; nucleoside kinase activity; protein binding; thymidine kinase activity; zinc ion binding

Biological Process: deoxyribonucleoside monophosphate biosynthetic process; fetal process involved in parturition; gut development; liver development; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide biosynthetic process; phosphorylation; protein homotetramerization; pyrimidine base metabolic process; pyrimidine nucleoside salvage; response to copper ion; response to cortisol stimulus; response to nutrient levels; response to toxin; skeletal muscle cell proliferation; thymidine metabolic process