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TOX Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248139

Some high-mobility group (HMG) box proteins contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG… More details

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Product Overview

Product Name
TOX, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TOX
Product Gene Name
Product Synonym Names
Anti-TOX Antibody (N-Terminus) IHC-plus; TOX; KIAA0808; TOX1; Human TOX
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human TOX. No alternatively spliced transcript variants have been observed.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
57,513 Da
OMIM
606863
3D Structure
ModBase 3D Structure for O94900
Target Species
Human
Immunogen Description
A 17 amino acid peptide near the amino terminus of human TOX.
Immunogen Type
Synthetic peptide
Immunogen
TOX antibody was raised against a 17 amino acid peptide near the amino terminus of human TOX.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-TOX antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TOX antibody
IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: TOX antibody can be used for detection of TOX by Western blot at 1-2 ug/mL.

Immunohistochemistry (IHC) of anti-TOX antibody

Anti-TOX antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TOX Polyclonal Antibody – Cat# MBS248139

Immunofluorescence (IF) of anti-TOX antibody

Immunofluorescence of TOX in human colon tissue with TOX antibody at 20 ug/ml.
Rabbit Anti-TOX Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS248139

Western Blot (WB) of anti-TOX antibody

Western blot analysis of TOX in human colon tissue lysate with TOX antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-TOX Polyclonal Antibody, Western Blot (WB) – Cat# MBS248139

Other Notes

Small volumes of anti-TOX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TOX purchase

MBS248139 is an antibody targeting TOX. Also known as Rabbit Polyclonal to Human TOX. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TOX. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thymocyte selection-associated high mobility group box protein TOX
NCBI Official Synonym Full Names
thymocyte selection-associated high mobility group box
NCBI Official Symbol
TOX
NCBI Official Synonym Symbols
TOX1
UniProt Protein Name
Thymocyte selection-associated high mobility group box protein TOX
UniProt Synonym Protein Names
Thymus high mobility group box protein TOX
UniProt Gene Name
TOX
UniProt Synonym Gene Names
KIAA0808
UniProt Entry Name
TOX_HUMAN
NCBI Protein Information
thymocyte selection-associated high mobility group box protein TOX; thymus high mobility group box protein TOX

NCBI Summary for TOX

The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.[provided by RefSeq, Apr 2009]

UniProt Comments for TOX

TOX: May play a role in regulating T-cell development.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 8q12.1

Cellular Component: nucleus

Molecular Function: DNA binding; chromatin binding

Biological Process: chromatin remodeling; regulation of transcription, DNA-dependent

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TOX antibody

 Reference Product  PubMed Publications
 TBX21 antibody  >2 publications with TOX and TBX21
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