Rabbit Anti-TRA2A Polyclonal Antibody – Cat# MBS6357804

TRA2A Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TRA2A antibody detected the TRA2A protein (arrow).

TRA2A Antibody – Rabbit Polyclonal

Name: TRA2A Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6357804
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6357804

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TRA2A, Polyclonal Antibody

Full Product Name

TRA2A, ID (TRA2A, Transformer-2 protein homolog alpha, Transformer-2 protein homolog A) (Biotin)

Product Gene Name

anti-TRA2A antibody

Product Synonym Names

TRA2A; Transformer-2 protein homolog alpha; Transformer-2 protein homolog A

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

32,689 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (23544399..23571656, complement). Location: 7p15.3

OMIM

602718

3D Structure

ModBase 3D Structure for Q13595

Immunogen

TRA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-182 amino acids from the Central region of human TRA2A.

Conjugate

Biotin

Note

Preservative Free

Product Categories/Family for anti-TRA2A antibody

Antibodies; RNA Binding Proteins

Applications Tested/Suitable for anti-TRA2A antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-TRA2A antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-TRA2A antibody

Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006). Gevaert, K., et al. Proteomics 5(14):3589-3599(2005).

Other Notes

Small volumes of anti-TRA2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRA2A purchase

MBS6357804 is an antibody targeting TRA2A. Also known as TRA2A, ID (TRA2A, Transformer-2 protein homolog alpha, Transformer-2 protein homolog A) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRA2A. It may not necessarily be applicable to this product.

NCBI GI #

9558733

NCBI GeneID

29896

NCBI Accession #

NP_037425.1

UniProt Primary Accession #

Q13595

UniProt Related Accession #

Q13595

GenBank Nucleotide #

NM_013293.3

NCBI Official Full Name

transformer-2 protein homolog alpha

NCBI Official Synonym Full Names

transformer 2 alpha homolog (Drosophila)

NCBI Official Symbol

TRA2A

NCBI Official Synonym Symbols

AWMS1; HSU53209

UniProt Protein Name

Transformer-2 protein homolog alpha

UniProt Synonym Protein Names

Transformer-2 protein homolog A

Protein Family

Transformer-2 protein

UniProt Gene Name

TRA2A

UniProt Synonym Gene Names

TRA-2 alpha; TRA2-alpha

UniProt Entry Name

TRA2A_HUMAN

NCBI Protein Information

transformer-2 protein homolog alpha; Tra2alpha; TRA2-alpha; TRA-2 alpha; htra-2 alpha; htra-2-alpha; transformer-2 alpha; transformer-2 protein homolog A; putative MAPK activating protein PM24

NCBI Summary for TRA2A

This gene is a member of the transformer 2 homolog family and encodes a protein with two RS domains and an RRM (RNA recognition motif) domain. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Several alternatively spliced transcript variants of this gene have been described; however, the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for TRA2A

TRA2A: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 7p15.3

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome

Research Articles on TRA2A

1. findings show the inclusion of both HIV-1 exon 3 and vpr mRNA processing is promoted by an exonic splicing enhancer (ESEvpr) localized between exonic splicing silencer ESSV and 5'ss D3; the ESEvpr sequence was found to be bound by members of the Tra2 protein family

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TRA2A antibody

Products by Pathway	Pathway Diagram
Spliceosome Pathway antibodies	Spliceosome Pathway Diagram
Spliceosome Pathway antibodies	Spliceosome Pathway Diagram

Organs/Tissues associated with anti-TRA2A antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>1 publications with TRA2A and Brain