Rabbit Anti-TRAF3IP2 Polyclonal Antibody – Cat# MBS6357871

TRAF3IP2 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TRAF3IP2 antibody detected the TRAF3IP2 protein (arrow).

TRAF3IP2 Antibody – Rabbit Polyclonal

Name: TRAF3IP2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6357871
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6357871

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TRAF3IP2, Polyclonal Antibody

Full Product Name

TRAF3IP2, CT (TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6, Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, TRAF3-interacting protein 2) (FITC)

Product Gene Name

anti-TRAF3IP2 antibody

Product Synonym Names

TRAF3IP2; C6orf2; C6orf4; C6orf5; C6orf6; Adapter protein CIKS; Connection to IKK and SAPK/JNK; Nuclear factor NF-kappa-B activator 1; TRAF3-interacting protein 2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

63,585 Da

OMIM

phenotype 615527

3D Structure

ModBase 3D Structure for O43734

Immunogen

TRAF3IP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human TRAF3IP2.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-TRAF3IP2 antibody

Antibodies; Adapter Proteins

Applications Tested/Suitable for anti-TRAF3IP2 antibody

Western Blot (WB), FLISA

Application Notes for anti-TRAF3IP2 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-TRAF3IP2 antibody

Ellinghaus, E., et al. Nat. Genet. 42(11):991-995(2010). Giltiay, N.V., et al. J. Immunol. 185(1):99-109(2010). Liu, C., et al. Sci Signal 2 (92), RA63 (2009): Li, X. Cytokine 41(2):105-113(2008). Huang, F., et al. J. Immunol. 179(10):6504-6513(2007).

Other Notes

Small volumes of anti-TRAF3IP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAF3IP2 purchase

MBS6357871 is an antibody targeting TRAF3IP2. Also known as TRAF3IP2, CT (TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6, Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, TRAF3-interacting protein 2) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAF3IP2. It may not necessarily be applicable to this product.

NCBI GI #

256017207

NCBI GeneID

10758

NCBI Accession #

NP_679211.2

UniProt Primary Accession #

O43734

UniProt Secondary Accession #

Q5R3A3; Q7Z6Q1; Q7Z6Q2; Q7Z6Q3; Q9H5W2; Q9H6Y3; Q9NS14; Q9UG72; B2RAY9; E1P555

UniProt Related Accession #

O43734

GenBank Nucleotide #

NM_147686.4

NCBI Official Full Name

adapter protein CIKS isoform 2

NCBI Official Synonym Full Names

TRAF3 interacting protein 2

NCBI Official Symbol

TRAF3IP2

NCBI Official Synonym Symbols

ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; PSORS13

UniProt Protein Name

Adapter protein CIKS

UniProt Synonym Protein Names

Connection to IKK and SAPK/JNK; Nuclear factor NF-kappa-B activator 1; ACT1; TRAF3-interacting protein 2

Protein Family

Adapter protein

UniProt Gene Name

TRAF3IP2

UniProt Synonym Gene Names

C6orf2; C6orf4; C6orf5; C6orf6; ACT1

UniProt Entry Name

CIKS_HUMAN

NCBI Protein Information

adapter protein CIKS

UniProt Comments for TRAF3IP2

TRAF3IP2: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK. Defects in TRAF3IP2 are the cause of susceptibility to psoriasis type 13 (PSORS13). PSORS13 is a common, chronic inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 6q21

Molecular Function: protein binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; immunoglobulin secretion; B cell apoptosis; humoral immune response

Disease: Candidiasis, Familial, 8; Psoriasis 13, Susceptibility To

Research Articles on TRAF3IP2

1. Four genes-ACT1, PIN1, DNMT1 and NTN1-emerged as having roles in pathways that may influence Primary Biliary Cholangitis pathogenesis in British Columbia First Nations people.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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