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TRNAU1AP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6358760

TRNAU1AP is involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May… More details

$1060 / 0.2 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
TRNAU1AP, Polyclonal Antibody
Full Product Name
TRNAU1AP, ID (TRNAU1AP, SECP43, TRSPAP1, tRNA selenocysteine 1-associated protein 1, SECp43, tRNA selenocysteine-associated protein 1) (APC)
Product Gene Name
Product Synonym Names
TRNAU1AP; SECP43; TRSPAP1; tRNA selenocysteine 1-associated protein 1; SECp43; tRNA selenocysteine-associated protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
20,403 Da
3D Structure
ModBase 3D Structure for Q9NX07
Immunogen
TRNAU1AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the Central region of human TRNAU1AP.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-TRNAU1AP antibody

Applications Tested/Suitable for anti-TRNAU1AP antibody
Western Blot (WB), FLISA
Application Notes for anti-TRNAU1AP antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-TRNAU1AP antibody

TRNAU1AP Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TRNAU1AP antibody detected the TRNAU1AP protein (arrow).
Rabbit Anti-TRNAU1AP Polyclonal Antibody – Cat# MBS6358760

Product References and Citations for anti-TRNAU1AP antibody

Small-Howard, A., et al. Mol. Cell. Biol. 26(6):2337-2346(2006). Xu, X.M., et al. J. Biol. Chem. 280(50):41568-41575(2005). Ding, F., et al. RNA 5(12):1561-1569(1999).

Other Notes

Small volumes of anti-TRNAU1AP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRNAU1AP purchase

MBS6358760 is an antibody targeting TRNAU1AP. Also known as TRNAU1AP, ID (TRNAU1AP, SECP43, TRSPAP1, tRNA selenocysteine 1-associated protein 1, SECp43, tRNA selenocysteine-associated protein 1) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRNAU1AP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tRNA selenocysteine 1-associated protein 1
NCBI Official Synonym Full Names
tRNA selenocysteine 1 associated protein 1
NCBI Official Symbol
TRNAU1AP
NCBI Official Synonym Symbols
SECP43; PRO1902; TRSPAP1
UniProt Protein Name
tRNA selenocysteine 1-associated protein 1
UniProt Synonym Protein Names
SECp43; tRNA selenocysteine-associated protein 1
UniProt Gene Name
TRNAU1AP
UniProt Synonym Gene Names
SECP43; TRSPAP1
UniProt Entry Name
TSAP1_HUMAN
NCBI Protein Information
tRNA selenocysteine 1-associated protein 1; tRNA selenocysteine associated protein 1; tRNA selenocysteine-associated protein 1; tRNA selenocysteine associated protein (SECP43)

UniProt Comments for TRNAU1AP

Function: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis

By similarity. Ref.5

Subunit structure: Component of the tRNA(Sec) complex composed at least of EEFSEC, SECISBP2, SEPHS1, SEPSECS, TRNAU1AP and tRNA(Sec). Found in a complex with tRNA(Sec). Interacts with SEPSECS. Associates with mRNP and/or polysomes

By similarity. Found in a complex with EEFSEC, SECISBP2, TRNAU1AP and tRNA(Sec). Ref.5

Subcellular location: Nucleus

By similarity. Cytoplasm

By similarity. Note: Abundant in the nucleus

By similarity.

Sequence similarities: Belongs to the RRM TRSPAP family.Contains 2 RRM (RNA recognition motif) domains.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TRNAU1AP antibody

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