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TSR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7053033

MBS7053033 is an antibody targeting TSR2. Also known as TSR2 Antibody. Reactive in Human. Host: Rabbit. May be involved in 20S pre-rRNA processing. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TSR2, Polyclonal Antibody
Full Product Name
TSR2 Antibody
Product Gene Name
Product Synonym Names
Pre-rRNA-processing protein TSR2 homolog; TSR2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: TSR2 (MBS7053033)
HRP Conjugated Antibody: TSR2 (MBS7053034)
Matching Pairs
Unconjugated Antibody: TSR2 (MBS7053033)
FITC Conjugated Antibody: TSR2 (MBS7053035)
Molecular Weight
20,894 Da
OMIM
Z85987 Genomic DNA
3D Structure
ModBase 3D Structure for Q969E8
Immunogen
Recombinant Human Pre-rRNA-processing protein TSR2 homolog protein (1-191AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TSR2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TSR2 antibody
IHC: 1:20-1:200
IF: 1:50-1:200

Immunohistochemistry (IHC) of anti-TSR2 antibody

Immunohistochemistry of paraffin-embedded human lung tissue using MBS7053033 at dilution of 1:100
Rabbit Anti-TSR2 Polyclonal Antibody – Cat# MBS7053033

Immunohistochemistry (IHC) of anti-TSR2 antibody

Immunohistochemistry of paraffin-embedded human heart tissue using MBS7053033 at dilution of 1:100
Rabbit Anti-TSR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7053033

Immunohistochemistry (IHC) of anti-TSR2 antibody

Immunofluorescent analysis of MCF-7 cells using MBS7053033 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-TSR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7053033

Western Blot (WB) of anti-TSR2 antibody

Western Blot
Positive WB detected in: HEK293 whole cell lysate
All lanes: TSR2 antibody at 2ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 21 KDa
Observed band size: 21 KDa
Rabbit Anti-TSR2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS7053033

Other Notes

Small volumes of anti-TSR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TSR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pre-rRNA-processing protein TSR2 homolog isoform a
NCBI Official Synonym Full Names
TSR2, ribosome maturation factor
NCBI Official Symbol
TSR2
NCBI Official Synonym Symbols
WGG1; DBA14; DT1P1A10
UniProt Protein Name
Pre-rRNA-processing protein TSR2 homolog
UniProt Gene Name
TSR2
NCBI Protein Information
pre-rRNA-processing protein TSR2 homolog

NCBI Summary for TSR2

The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016]

UniProt Comments for TSR2

TSR2: May be involved in 20S pre-rRNA processing (Potential). Belongs to the TSR2 family.

Chromosomal Location of Human Ortholog: Xp11.22

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Disease: Diamond-blackfan Anemia 14 With Mandibulofacial Dysostosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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